ArticlePLoS computational biology2021
Hybrid dedicated and distributed coding in PMd/M1 provides separation and interaction of bilateral arm signals.
Article in PLoS computational biology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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Who cites it
6 citing papers in PubMed.
- Learning-related population dynamics in right and left dorsal premotor cortex during typing skill acquisition.bioRxiv : the preprint server for biology · 2026Article
- Time-dependent facilitation of homologous actions.Experimental brain research · 2026Article
- Article
- Pseudo-linear summation explains neural geometry of multi-finger movements in human premotor cortex.Nature communications · 2025Article
- Differential contribution of sensorimotor cortex and subthalamic nucleus to unimanual and bimanual hand movements.Cerebral cortex (New York, N.Y. : 1991) · 2024Article
- Hybrid dedicated and distributed coding in PMd/M1 provides separation and interaction of bilateral arm signals.PLoS computational biology · 2021Article
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Authors and funding
5 authors.
Funding
Abstract
Pronounced activity is observed in both hemispheres of the motor cortex during preparation and execution of unimanual movements. The organizational principles of bi-hemispheric signals and the functions they serve throughout motor planning remain unclear. Using an instructed-delay reaching task in monkeys, we identified two components in population responses spanning PMd and M1. A "dedicated" component, which segregated activity at the level of individual units, emerged in PMd during preparation. It was most prominent following movement when M1 became strongly engaged, and principally involved the contralateral hemisphere. In contrast to recent reports, these dedicated signals solely accounted for divergence of arm-specific neural subspaces. The other "distributed" component mixed signals for each arm within units, and the subspace containing it did not discriminate between arms at any stage. The statistics of the population response suggest two functional aspects of the cortical network: one that spans both hemispheres for supporting preparatory and ongoing processes, and another that is predominantly housed in the contralateral hemisphere and specifies unilateral output.
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Registered trials
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