Evidence map›Paper›PMID 34809686›Full record

ReviewItalian journal of pediatrics2021

Pediatric eosinophilic esophagitis: a review for the clinician.

Simona Barni, Stefania Arasi, Carla Mastrorilli, Luca Pecoraro, Mattia Giovannini, Francesca Mori, Lucia Liotti, Francesca Saretta, Riccardo Castagnoli, Lucia Caminiti and 2 more

Open access · goldAbstract readReview
In one paragraph

Review in Italian journal of pediatrics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
6.9field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 50 citations in OpenAlex.

  1. Trial
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Observational
  9. Review
  10. Dysphagia Among Children-A Single-Center Experience.Journal of clinical medicine · 2025
    Article
  11. Article
  12. Observational
  13. A clinical predictive model identifies pediatric patients at risk for eosinophilic esophagitis.Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver · 2024
    Article
  14. Review
  15. Review
  16. Article
  17. Article
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 8 institutions in 2 countries.

Simona BarniAllergy Unit, Department of Pediatrics, Meyer Children's University Hospital, Florence, Italy.
Stefania ArasiPredictive and Preventive Medicine Research Unit, Multifactorial and Systemic Diseases Research Area, Pediatric Allergy Unit, Bambino Gesù Children's Hospital IRCCS, Rome, Italy.
Carla MastrorilliPediatric Unit and Emergency, University Hospital Consortium Corporation Polyclinic of Bari, Pediatric Hospital Giovanni XXIII, Bari, Italy.
Luca PecoraroDepartment of Medicine, University of Verona, Policlinico GB Rossi, Verona, Italy.
Mattia GiovanniniAllergy Unit, Department of Pediatrics, Meyer Children's University Hospital, Florence, Italy. mattiag88@hotmail.it.ORCID http://orcid.org/0000-0001-9568-6882
Francesca MoriAllergy Unit, Department of Pediatrics, Meyer Children's University Hospital, Florence, Italy.
Lucia LiottiPediatric Unit, Senigallia Hospital, Senigallia, Italy.
Francesca SarettaPediatric Department, Latisana-Palmanova Hospital, Azienda Sanitaria Universitaria Friuli Centrale, Udine, Italy.
Riccardo CastagnoliDepartment of Pediatrics, Pediatric Clinic, Fondazione IRCCS Policlinico San Matteo, University of Pavia, Pavia, Italy.
Lucia CaminitiDepartment of Human Pathology in Adult and Development Age "Gaetano Barresi", Allergy Unit, Department of Pediatrics, AOU Policlinico Gaetano Martino, Messina, Italy.
Antonella Cianferoni *Pediatrics Department, Perelman School of Medicine, University of Pennsylvania, Philadelphia, USA.
Elio Novembre *Allergy Unit, Department of Pediatrics, Meyer Children's University Hospital, Florence, Italy.
Meyer Children's Hospital · ITBambino Gesù Children's Hospital · ITChildren's Hospital of Philadelphia · USIstituto Ortopedico Gaetano Pini · ITOspedale di Latisana · ITUniversity of Parma · ITUniversity of Pavia · ITUniversity of Verona · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Eosinophilic esophagitis (EoE) is a chronic clinical-pathologic disease characterized by eosinophilic infiltration of the esophageal epithelium with esophageal dysfunction symptoms.EoE can occur at any age and has different clinical manifestations depending on the age onset.To date, esophago-gastroduodenal endoscopy (EGD) with biopsy is the gold-standard for EoE diagnosis.According to the recent consensus guidelines, proton pump inhibitors, corticosteroids and elimination diets could be a first-line therapy option. The aim of the treatment is clinical and histological remission for preventing long-lasting untreatable fibrosis.A multidisciplinary approach (allergist, gastroenterology, dietitian, and pathologist) is recommended for managing patients affected by EoE, given the complexity of its treatment.This review will provide a practical guide to assist pediatricians treating children with EoE.Moreover, it highlights the unmet needs in diagnosis and treatment that require urgent attention from the scientific community in the aim of improving the management of patients with EoE.

Indexed as

Eosinophilic EsophagitisAlgorithmsDietDilatationEnvironmental ExposureEsophagoscopyGenetic Predisposition to DiseaseGlucocorticoidsHumansPediatricsProton Pump InhibitorsRisk FactorsGlucocorticoidsProton Pump Inhibitors

Identifiers

PMID34809686
PMCPMC8609874
OpenAlexW3217511170

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.