Evidence map›Paper›PMID 34815383›Full record

ArticleTranslational psychiatry2021

Cortical complexity in world trade center responders with chronic posttraumatic stress disorder.

Minos Kritikos, Sean A P Clouston, Chuan Huang, Alison C Pellecchia, Stephanie Mejia-Santiago, Melissa A Carr, Roman Kotov, Roberto G Lucchini, Samuel E Gandy, Evelyn J Bromet and 1 more

Open access · goldAbstract read
In one paragraph

Article in Translational psychiatry, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 1 pooled it
2.3field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 1 synthesis or guideline pooled it, 25 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Mechanistic signatures of comorbid PTSD with cognitive impairment implicate cortisol-induced neural toxicity.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2026
    Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Cognitive Function among World Trade Center-Exposed Community Members with Mental Health Symptoms.International journal of environmental research and public health · 2022
    Article
  17. Article
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

Minos KritikosProgram in Public Health and Department of Family, Population, and Preventive Medicine, Renaissance School of Medicine at Stony Brook University, Stony Brook, NY, USA.ORCID http://orcid.org/0000-0003-2710-0717
Sean A P CloustonProgram in Public Health and Department of Family, Population, and Preventive Medicine, Renaissance School of Medicine at Stony Brook University, Stony Brook, NY, USA. sean.clouston@stonybrookmedicine.edu.ORCID http://orcid.org/0000-0002-6124-0329
Chuan HuangDepartment of Radiology, Renaissance School of Medicine at Stony Brook, Stony Brook, NY, USA.ORCID http://orcid.org/0000-0001-6052-0663
Alison C PellecchiaWorld Trade Center Health and Wellness Program, Renaissance School of Medicine at Stony Brook University, Stony Brook, NY, USA.ORCID http://orcid.org/0000-0003-0150-289X
Stephanie Mejia-SantiagoWorld Trade Center Health and Wellness Program, Renaissance School of Medicine at Stony Brook University, Stony Brook, NY, USA.
Melissa A CarrWorld Trade Center Health and Wellness Program, Renaissance School of Medicine at Stony Brook University, Stony Brook, NY, USA.ORCID http://orcid.org/0000-0002-0870-6628
Roman KotovDepartment of Psychiatry, Renaissance School of Medicine at Stony Brook University, Stony Brook, NY, USA.
Roberto G LucchiniDepartment of Environmental Health Sciences, Robert Stempel School of Public Health, Florida International University, Miami, FL, USA.ORCID http://orcid.org/0000-0002-9723-0237
Samuel E GandyDepartment of Neurology, Icahn School of Medicine at Mount Sinai, New York, NY, USA.ORCID http://orcid.org/0000-0001-6455-4721
Evelyn J BrometDepartment of Psychiatry, Renaissance School of Medicine at Stony Brook University, Stony Brook, NY, USA.
Benjamin J LuftWorld Trade Center Health and Wellness Program, Renaissance School of Medicine at Stony Brook University, Stony Brook, NY, USA.ORCID http://orcid.org/0000-0001-9008-7004
Stony Brook School · USFlorida International University · USIcahn School of Medicine at Mount Sinai · US

Funding

VESICULAR LOCALIZATION AND FUNCTION OF PRESENILIN 1 FRAGMENTP50AG005138 · NIA · MOUNT SINAI SCHOOL OF MEDICINE OF NYU · PI GROSSMAN, HILLEL · 1985 to 2019
$37.9M
Research Education ComponentP30AG066514 · NIA · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI Margaret Sewell · 2020 to 2026
$31.0M
A lifecourse approach to PTSD and cognitive aging: A cohort of 9/11 respondersR01AG049953 · NIA · STATE UNIVERSITY NEW YORK STONY BROOK · PI CLOUSTON, SEAN · 2015 to 2024
$11.0M
Burden and change in Alzheimers disease neuropathology in aging World Trade Center respondersR01AG067590 · NIA · STATE UNIVERSITY NEW YORK STONY BROOK · PI CLOUSTON, SEAN, KUAN, PEI-FEN · 2021 to 2025
$4.0M
Structural and Functional Neuroimaging of Post Traumatic Stress Disorder and Cognitive Impairment in World Trade Center RespondersU01OH011314 · OH · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI LUCCHINI, ROBERTO G, LUFT, BENJAMIN J · 2016 to 2019
$2.4M
NIA NIH HHS P30 AG066514NIA NIH HHS P50 AG005138NIA NIH HHS R01 AG049953NIA NIH HHS R01 AG067590NIOSH CDC HHS U01 OH011314
6 · The paper itself

Abstract

Approximately 23% of World Trade Center (WTC) responders are experiencing chronic posttraumatic stress disorder (PTSD) associated with their exposures at the WTC following the terrorist attacks of 9/11/2001, which has been demonstrated to be a risk factor for cognitive impairment raising concerns regarding their brain health. Cortical complexity, as measured by analyzing Fractal Dimension (FD) from T

Indexed as

Emergency RespondersSeptember 11 Terrorist AttacksStress Disorders, Post-TraumaticCase-Control StudiesHumansRisk Factors

Identifiers

PMID34815383
PMCPMC8611009
OpenAlexW3217795607

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.