Evidence map›Paper›PMID 34819041›Full record

ArticleBMC genomics2021

Profile of gene expression changes during estrodiol-17β-induced feminization in the Takifugu rubripes brain.

Xufang Shen, Hongwei Yan, Jieming Jiang, Weiyuan Li, Yuyu Xiong, Qi Liu, Ying Liu

Open access · goldAbstract read
In one paragraph

Article in BMC genomics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.0field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 10 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Xufang ShenCollege of Life Sciences, Liaoning Normal University, Dalian, 116029, Liaoning, China.
Hongwei YanCollege of Fisheries and Life Science, Dalian Ocean University, Dalian, 116023, Liaoning, China. yanhongwei_1985@hotmail.com.
Jieming JiangKey Laboratory of Environment Controlled Aquaculture (Dalian Ocean University) Ministry of Education, Dalian, 116023, China.
Weiyuan LiCollege of Fisheries and Life Science, Dalian Ocean University, Dalian, 116023, Liaoning, China.
Yuyu XiongKey Laboratory of Environment Controlled Aquaculture (Dalian Ocean University) Ministry of Education, Dalian, 116023, China.
Qi LiuCollege of Marine Science and Environment Engineering, Dalian Ocean University, Dalian, 116023, Liaoning, China. liuqisunson@163.com.
Ying LiuKey Laboratory of Environment Controlled Aquaculture (Dalian Ocean University) Ministry of Education, Dalian, 116023, China.
Dalian Ocean University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAs the critical tissue of the central nervous system, the brain has been found to be involved in gonad development. Previous studies have suggested that gonadal fate may be affected by the brain. Identifying brain-specific molecular changes that occur during estrodiol-17β (E

resultsIn this study, the differential transcriptomic responses of the Takifugu rubripes larvae brain were compared after E

conclusionA number of genes and pathways were identified in the brain of E

Indexed as

FeminizationTakifuguAnimalsBrainFemaleHumansMaleSex DifferentiationTranscriptomeBrainEstradiol-17βSex differentiationTakifugu rubripesTranscriptome analysis

Identifiers

PMID34819041
PMCPMC8614003
OpenAlexW3207315489

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.