Evidence map›Paper›PMID 34819084›Full record

ReviewJournal of nanobiotechnology2021

Recent developments in mesoporous polydopamine-derived nanoplatforms for cancer theranostics.

Menglu Zhu, Yi Shi, Yifan Shan, Junyan Guo, Xuelong Song, Yuhua Wu, Miaolian Wu, Yan Lu, Wei Chen, Xiaoling Xu and 1 more

Abstract readReview
In one paragraph

Review in Journal of nanobiotechnology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers.

0numbers the graph read from it
0cells of the map it votes in
40citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

40 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Menglu Zhu *The Fourth Affiliated Hospital, Zhejiang University School of Medicine, 322000, Yiwu, Zhejiang, People's Republic of China.
Yi Shi *Longhua Hospital, Shanghai University of Traditional Chinese Medicine, 200032, Shanghai, People's Republic of China.
Yifan ShanThe Fourth Affiliated Hospital, Zhejiang University School of Medicine, 322000, Yiwu, Zhejiang, People's Republic of China.
Junyan GuoThe Fourth Affiliated Hospital, Zhejiang University School of Medicine, 322000, Yiwu, Zhejiang, People's Republic of China.
Xuelong SongThe Fourth Affiliated Hospital, Zhejiang University School of Medicine, 322000, Yiwu, Zhejiang, People's Republic of China.
Yuhua WuThe Fourth Affiliated Hospital, Zhejiang University School of Medicine, 322000, Yiwu, Zhejiang, People's Republic of China.
Miaolian WuThe Fourth Affiliated Hospital, Zhejiang University School of Medicine, 322000, Yiwu, Zhejiang, People's Republic of China.
Yan LuThe Fourth Affiliated Hospital, Zhejiang University School of Medicine, 322000, Yiwu, Zhejiang, People's Republic of China.
Wei ChenLonghua Hospital, Shanghai University of Traditional Chinese Medicine, 200032, Shanghai, People's Republic of China. cwdoctor@163.com.
Xiaoling XuShulan International Medical College, Zhejiang Shuren University, 310004, Hangzhou, Zhejiang, People's Republic of China. ziyao1988@zju.edu.cn.
Longguang TangThe Fourth Affiliated Hospital, Zhejiang University School of Medicine, 322000, Yiwu, Zhejiang, People's Republic of China. tanglongguang@zju.edu.cn.

Funding

Jinhua Science and Technology Bureau 2020-4-117Natural Science Foundation of Zhejiang Province LY18H300005
6 · The paper itself

Abstract

Polydopamine (PDA), which is derived from marine mussels, has excellent potential in early diagnosis of diseases and targeted drug delivery owing to its good biocompatibility, biodegradability, and photothermal conversion. However, when used as a solid nanoparticle, the application of traditional PDA is restricted because of the low drug-loading and encapsulation efficiencies of hydrophobic drugs. Nevertheless, the emergence of mesoporous materials broaden our horizon. Mesoporous polydopamine (MPDA) has the characteristics of a porous structure, simple preparation process, low cost, high specific surface area, high light-to-heat conversion efficiency, and excellent biocompatibility, and therefore has gained considerable interest. This review provides an overview of the preparation methods and the latest applications of MPDA-based nanodrug delivery systems (chemotherapy combined with radiotherapy, photothermal therapy combined with chemotherapy, photothermal therapy combined with immunotherapy, photothermal therapy combined with photodynamic/chemodynamic therapy, and cancer theranostics). This review is expected to shed light on the multi-strategy antitumor therapy applications of MPDA-based nanodrug delivery systems.

Indexed as

IndolesNanoparticle Drug Delivery SystemNeoplasmsPhotothermal TherapyPolymersTheranostic NanomedicineAnimalsAntineoplastic AgentsCell Line, TumorHumansImmunotherapyMiceNanostructuresAntineoplastic AgentsIndolesNanoparticle Drug Delivery SystempolydopaminePolymersCancer theranosticsImmunotherapyMPDANanodrug delivery systemsPhotothermal therapy

Identifiers

PMID34819084
PMCPMC8613963

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.