Evidence mapPaperPMID 34820573Full record

ReviewBioactive materials2022

Cell-matrix reciprocity in 3D culture models with nonlinear elasticity.

Kaizheng Liu, Maury Wiendels, Hongbo Yuan, Changshun Ruan, Paul H J Kouwer

Open access · goldAbstract readReview
In one paragraph

Review in Bioactive materials, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed
5.8field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed, 70 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Review
  5. Article
  6. Review
  7. Review
  8. Bioinspired Collagen/κ-Carrageenan 3D Matrix forACS biomaterials science & engineering · 2025
    Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Review
  14. ACS applied materials & interfaces · 2024
    Article
  15. Article
  16. Review
  17. Nanocolloidal hydrogel mimics the structure and nonlinear mechanical properties of biological fibrous networks.Proceedings of the National Academy of Sciences of the United States of America · 2023
    Article
  18. Synthetic living materials in cancer biology.Nature reviews bioengineering · 2023
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 3 countries.

Kaizheng LiuResearch Center for Human Tissue and Organs Degeneration, Institute of Biomedicine and Biotechnology, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen, 518055, PR China.
Maury WiendelsRadboud University, Institute for Molecules and Materials, Heyendaalseweg 135, 6525 AJ, Nijmegen, the Netherlands.
Hongbo YuanInstitute of Biophysics, Hebei University of Technology, Tianjin, 300401, PR China.
Changshun RuanResearch Center for Human Tissue and Organs Degeneration, Institute of Biomedicine and Biotechnology, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen, 518055, PR China.
Paul H J KouwerRadboud University, Institute for Molecules and Materials, Heyendaalseweg 135, 6525 AJ, Nijmegen, the Netherlands.
Radboud University Nijmegen · NLChinese Academy of Sciences · CNHebei University of Technology · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Three-dimensional (3D) matrix models using hydrogels are powerful tools to understand and predict cell behavior. The interactions between the cell and its matrix, however is highly complex: the matrix has a profound effect on basic cell functions but simultaneously, cells are able to actively manipulate the matrix properties. This (mechano)reciprocity between cells and the extracellular matrix (ECM) is central in regulating tissue functions and it is fundamentally important to broadly consider the biomechanical properties of the

Indexed as

Artificial extracellular matricesCollagenFibrinMechanical reciprocityPolyisocyanides

Identifiers

PMID34820573
PMCPMC8586441
OpenAlexW3193342332

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.