Evidence mapPaperPMID 34825525Full record

ReviewAdvanced science (Weinheim, Baden-Wurttemberg, Germany)2022

Emerging Theranostic Nanomaterials in Diabetes and Its Complications.

Yuntao Liu, Siqi Zeng, Wei Ji, Huan Yao, Lin Lin, Haiying Cui, Hélder A Santos, Guoqing Pan

Open access · goldAbstract readReview
In one paragraph

Review in Advanced science (Weinheim, Baden-Wurttemberg, Germany), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 49 papers.

0numbers the graph read from it
0cells of the map it votes in
49citing papers in PubMed
7.3field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

49 citing papers in PubMed, 137 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Review
  6. Review
  7. Review
  8. Review
  9. Article
  10. Review
  11. Liraglutide-Conjugated Poly(methyl vinyl ether-ACS applied materials & interfaces · 2025
    Article
  12. Article
  13. Review
  14. Article
  15. Article
  16. Review
  17. Article
  18. Article
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 3 countries.

Yuntao LiuSchool of Food & Biological Engineering, Jiangsu University, Zhenjiang, 212013, China.
Siqi ZengCollege of Food Science, Sichuan Agricultural University, Yaan, 625014, China.
Wei JiDepartment of Pharmaceutics, School of Pharmacy, Jiangsu University, Zhenjiang, Jiangsu, 212013, China.
Huan YaoSichuan Institute of Food Inspection, Chengdu, 610097, China.
Lin LinSchool of Food & Biological Engineering, Jiangsu University, Zhenjiang, 212013, China.
Haiying CuiSchool of Food & Biological Engineering, Jiangsu University, Zhenjiang, 212013, China.
Hélder A SantosDrug Research Program, Division of Pharmaceutical Chemistry and Technology, Faculty of Pharmacy, University of Helsinki, Helsinki, FI-00014, Finland.ORCID 0000-0001-7850-6309
Guoqing PanInstitute for Advanced Materials, School of Materials Science and Engineering, Jiangsu University, Zhenjiang, Jiangsu, 212013, China.ORCID 0000-0001-5187-796X
Jiangsu University · CNSichuan Agricultural University · CNSichuan Entry-Exit Inspection and Quarantine Bureau · CNUniversity Medical Center Groningen · NL

Funding

Academy of Finland 317042Academy of Finland 331151Home for Researchers editorial teamInnovation and Entrepreneurship Program of Jiangsu ProvinceNational Key Research and Development Program of China 2019YFA0112000National Natural Science Foundation of China 21875092National Natural Science Foundation of China 31801629Sichuan Science and Technology Program 2020YJ0156Sigrid Jusélius Foundation"Six Talent Peaks" program of Jiangsu Province 2018-XCL-013Terveyden Tutkimuksen Toimikunta 317042
6 · The paper itself

Abstract

Diabetes mellitus (DM) refers to a group of metabolic disorders that are characterized by hyperglycemia. Oral subcutaneously administered antidiabetic drugs such as insulin, glipalamide, and metformin can temporarily balance blood sugar levels, however, long-term administration of these therapies is associated with undesirable side effects on the kidney and liver. In addition, due to overproduction of reactive oxygen species and hyperglycemia-induced macrovascular system damage, diabetics have an increased risk of complications. Fortunately, recent advances in nanomaterials have provided new opportunities for diabetes therapy and diagnosis. This review provides a panoramic overview of the current nanomaterials for the detection of diabetic biomarkers and diabetes treatment. Apart from diabetic sensing mechanisms and antidiabetic activities, the applications of these bioengineered nanoparticles for preventing several diabetic complications are elucidated. This review provides an overall perspective in this field, including current challenges and future trends, which may be helpful in informing the development of novel nanomaterials with new functions and properties for diabetes diagnosis and therapy.

Indexed as

Diabetes ComplicationsDiabetes MellitusHumansHypoglycemic AgentsNanostructuresPrecision MedicineHypoglycemic Agentsacetone sensingantioxidantdiabetic complicationsglucose detectionnanocarrierwound healing

Identifiers

PMID34825525
PMCPMC8787437
OpenAlexW3216228550

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.