Evidence map›Paper›PMID 34826682›Full record

ReviewCurrent opinion in biotechnology2021

Flexible optoelectric neural interfaces.

Zabir Ahmed, Jay W Reddy, Mohammad H Malekoshoaraie, Vahid Hassanzade, Ibrahim Kimukin, Vishal Jain, Maysamreza Chamanzar

Abstract readReview
In one paragraph

Review in Current opinion in biotechnology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Three-dimensional microelectrode arrays forBiomedical engineering letters · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Zabir AhmedDepartment of Electrical and Computer Engineering, Carnegie Mellon University, Pittsburgh, PA 15213, United States.
Jay W ReddyDepartment of Electrical and Computer Engineering, Carnegie Mellon University, Pittsburgh, PA 15213, United States.
Mohammad H MalekoshoaraieDepartment of Electrical and Computer Engineering, Carnegie Mellon University, Pittsburgh, PA 15213, United States.
Vahid HassanzadeDepartment of Electrical and Computer Engineering, Carnegie Mellon University, Pittsburgh, PA 15213, United States.
Ibrahim KimukinDepartment of Electrical and Computer Engineering, Carnegie Mellon University, Pittsburgh, PA 15213, United States.
Vishal JainDepartment of Electrical and Computer Engineering, Carnegie Mellon University, Pittsburgh, PA 15213, United States.
Maysamreza ChamanzarDepartment of Electrical and Computer Engineering, Carnegie Mellon University, Pittsburgh, PA 15213, United States. Electronic address: mchamanzar@cmu.edu.

Funding

Smart Dura: A Functional Large-scale, High-Density Optoelectric Dura for Non-Human PrimatesR01NS116464 · NINDS · CARNEGIE-MELLON UNIVERSITY · PI CHAMANZAR, MAYSAMREZA · 2020 to 2024
$2.0M
Multimodal Stainless Steel Neural Interfaces for Large-scale Recording and Modulation in Large AnimalsRF1NS113303 · NINDS · CARNEGIE-MELLON UNIVERSITY · PI CHAMANZAR, MAYSAMREZA · 2019 to 2019
$912k
NINDS NIH HHS R01 NS116464NINDS NIH HHS RF1 NS113303
6 · The paper itself

Abstract

Understanding the neural basis of brain function and dysfunction and designing effective therapeutics require high resolution targeted stimulation and recording of neural activity. Optical methods have been recently developed for neural stimulation as well as functional and structural imaging. These methods call for implantable devices to deliver light into the neural tissue at depth with high spatiotemporal resolution. To address this need, rigid and flexible neurophotonic implants have been recently designed. This article reviews the state-of-the-art flexible passive and active penetrating optical neural probes developed for light delivery with minimal damage to the tissue. Passive and active flexible neurophotonic implants are compared and insights about future directions are provided.

Indexed as

Prostheses and Implants

Identifiers

PMID34826682
PMCPMC9741731

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.