Evidence map›Paper›PMID 34826770›Full record

ArticleArchives of gerontology and geriatrics

Longitudinal physical performance and blood pressure changes in older women: Findings form the women's health initiative.

Deepika R Laddu, Michael J LaMonte, Bernhard Haring, Hajwa Kim, Peggy Cawthon, Jennifer W Bea, Hailey Banack, Jane A Cauley, Matthew A Allison, Lisa Warsinger Martin and 4 more

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Archives of gerontology and geriatrics. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.8field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 10 citations in OpenAlex.

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  6. Promoting healthy cardiovascular aging: emerging topics.The journal of cardiovascular aging · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 11 institutions in 2 countries.

Deepika R LadduDepartment of Physical Therapy, College of Applied Health Sciences, University of Illinois at Chicago, Chicago, IL, USA. Electronic address: dladdu@uic.edu.
Michael J LaMonteDepartment of Epidemiology and Environmental Health, School of Public Health and Health Professions, University at Buffalo - SUNY, New York, Buffalo, New York, USA.
Bernhard HaringDepartment of Medicine, Division of Cardiology, University Heart Center Graz, Graz, Austria; Department of Internal Medicine I/Cardiology, University of Würzburg, Würzburg, Germany.
Hajwa KimUniversity of Illinois at Chicago, Center for Clinical and Translational Science, Biostatistics Core, 914 S. Wood Street, Chicago, IL, USA.
Peggy CawthonCalifornia Pacific Medical Center Research Institute, San Francisco, California, USA; Department of Epidemiology and Biostatics, University of California, San Francisco, CA, USA.
Jennifer W BeaDepartment of Health Promotion Sciences, Mel and Enid Zuckerman College of Public Health, University of Arizona, Tucson, Arizona, USA.
Hailey BanackDepartment of Epidemiology and Environmental Health, School of Public Health and Health Professions, University at Buffalo - SUNY, New York, Buffalo, New York, USA.
Jane A CauleyDepartment Of Epidemiology, University of Pittsburgh Graduate School of Public Health, Pittsburgh, PA, USA.
Matthew A AllisonDepartment of Family Medicine, University of California San Diego, San Diego, CA, USA.
Lisa Warsinger MartinDivision of Cardiology, School of Medicine and Health Sciences, George Washington University, Washington DC, USA.
Meryl S LeBoffEndocrine-Hypertension Division, Brigham and Women's Hospital, Boston, Mass, USA.
Marcia L StefanickStanford Prevention Research Center, School of Medicine, Stanford University, Stanford, CA, USA.
Shane A PhillipsDepartment of Physical Therapy, College of Applied Health Sciences, University of Illinois at Chicago, Chicago, IL, USA.
Jun MaDepartment of Medicine, University of Illinois at Chicago, 1747 W. Roosevelt Rd, Room 586 (MC 275), Chicago, IL, USA.
University of Illinois Chicago · USUniversity at Buffalo, State University of New York · USBrigham and Women's Hospital · USGeorge Washington University · USRoosevelt University · USStanford University · USUniversity of Arizona · USUniversity of California, San Diego · USUniversity of California, San Francisco · USUniversity of Pittsburgh · USUniversity of Würzburg · DE

Funding

University of Buffalo Clinical and Translational Science Institute - Supplement SchulyerUL1TR001412 · NCATS · STATE UNIVERSITY OF NEW YORK AT BUFFALO · PI MURPHY, TIMOTHY F · 2015 to 2024
$33.8M
The impact of a resistance training intervention on blood pressure control in older adults with SarcopeniaK01HL148503 · NHLBI · UNIVERSITY OF ILLINOIS AT CHICAGO · PI LADDU, DEEPIKA · 2019 to 2023
$901k
NCATS NIH HHS UL1 TR001412NHLBI NIH HHS HHSN268201100001INHLBI NIH HHS HHSN268201100002INHLBI NIH HHS HHSN268201100003INHLBI NIH HHS K01 HL148503NIA NIH HHS HHSN271201100004CWHI NIH HHS HHSN268201100001CWHI NIH HHS HHSN268201100002CWHI NIH HHS HHSN268201100003CWHI NIH HHS HHSN268201100004C
6 · The paper itself

Abstract

backgroundThis study evaluated the association between changes in physical performance and blood pressure (BP) (e.g., systolic [SBP], diastolic [DBP], pulse pressure) in older women.

methods5627 women (mean age 69.8 ± 3.7 y) with grip strength, chair stand, gait speed performance and clinic-measured BP at baseline and at least one follow-up (years 1, 3 or 6) were included. Generalized estimating equation analysis of multivariable models with standardized point estimates described the longitudinal association between physical performance and BP changes in the overall cohort, and in models stratified by baseline cardiovascular disease (CVD), time-varying antihypertensive medication use (none, ≥1) and enrollment age (65-69 y; 70-79 y).

resultsOverall, each z-score unit increment in grip strength was associated with 0.59 mmHg (95% CI 0.10, 1.08) higher SBP, and 0.39 mmHg (95% CI 0.11, 0.67) higher DBP. In stratified models, a standardized increment in grip strength was associated with higher SBP in women without CVD (0.81; 95% CI 0.23-1.39), among antihypertensive medication users (0.93; 95% CI 0.44, 1.41) and non-users (0.37; 95% CI 0.03, 0.71), and in those aged 65-69 y (0.64; 95% CI 0.04, 1.24). Similarly, a standardized increment in any of the three performance measures was associated with modestly higher DBP in antihypertensive medication users, and those aged 70-79 y. Associations between any performance measure and pulse pressure change were not significant.

conclusionThese results suggest a positive, and statistically significant relationship between physical performance and BP that appears to be influenced by CVD history, antihypertensive medication use, and age.

Indexed as

Cardiovascular DiseasesHypertensionAgedAntihypertensive AgentsBlood PressureFemaleHumansPhysical Functional PerformanceWomen's HealthAntihypertensive AgentsAgingBlood pressureChair standGait speedGrip strengthOlder womenPhysical functioningTrajectories

Identifiers

PMID34826770
PMCPMC8649052
OpenAlexW3213694195

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.