Evidence map›Paper›PMID 34827379›Full record

ArticleBrain sciences2021

Down Syndrome: Neuropsychological Phenotype across the Lifespan.

Margaret Pulsifer

Open access · goldAbstract readEditorial
In one paragraph

Article in Brain sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact, top 79% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

Margaret PulsiferDepartment of Psychiatry, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA.
Massachusetts General Hospital · US

Funding

National Centralized Repository for Alzheimer's Disease and Related Dementias (NCRAD)U24AG021886 · NIA · INDIANA UNIV-PURDUE UNIV AT INDIANAPOLIS · PI TATIANA M. FOROUD · 2002 to 2026
$119.8M
Project 3: Biomarkers for DS Clinical TrialsU19AG068054 · NIA · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI CHRISTIAN, BRADLEY T · 2020 to 2025
$103.7M
Effects of Hypoglossal Nerve Stimulation on Cognition & Language in Down SyndromeU01DC019279 · NIDCD · MASSACHUSETTS EYE AND EAR INFIRMARY · PI HARTNICK, CHRISTOPHER J, SKOTKO, BRIAN GARY · 2020 to 2024
$4.0M
NIA NIH HHS U19 AG068054NIA NIH HHS U24 AG021886NIDCD NIH HHS U01 DC019279
6 · The paper itself

Abstract

Down syndrome (DS), caused by triplication of chromosome 21, is the most common genetic cause of intellectual disability (ID), with an estimated incidence of one in 700 live births [...].

Identifiers

PMID34827379
PMCPMC8615974
OpenAlexW3207314543

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.