Evidence map›Paper›PMID 34828420›Full record

ArticleGenes2021

Circulatory

Reda Albadawy, Sara H A Agwa, Eman Khairy, Maha Saad, Naglaa El Touchy, Mohamed Othman, Mohamed El Kassas, Marwa Matboli

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Genes, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 3 pooled it
0.9field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 3 syntheses or guidelines pooled it, 16 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Review
  5. Jiangtang Decoction for Type 2 Diabetes and NAFLD: Integrative AnalysisEndocrine, metabolic & immune disorders drug targets · 2026
    Article
  6. Article
  7. Review
  8. Serum non-coding RNAs for diagnosis and stage of liver fibrosis.Journal of clinical laboratory analysis · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 2 countries.

Reda AlbadawyGastroentrology, Hepatology & Infectious Disease Department, Faculty of Medicine, Benha University, Benha 13736, Egypt.
Sara H A AgwaClinical Pathology Department, Molecular Genomics Unit of Medical Ain Shams Research Institute, School of Medicine, Ain Shams University, Cairo 11566, Egypt.
Eman KhairyMedicinal Biochemistry and Molecular Biology Department, Ain Shams University School of Medicine, Cairo 11566, Egypt.ORCID 0000-0002-2822-241X
Maha SaadBiochemistry Department, Faculty of Medicine, Modern University for Technology and Information, Cairo 12055, Egypt.
Naglaa El TouchyGastroentrology, Hepatology & Infectious Disease Department, Faculty of Medicine, Benha University, Benha 13736, Egypt.
Mohamed OthmanGastroenterology and Hepatology Section, Baylor College of Medicine, Houston, TX 77030, USA.
Mohamed El KassasEndemic Medicine and Hepato-Gastroenterology Department, Faculty of Medicine, Helwan University, Helwan 11792, Egypt.ORCID 0000-0002-3396-6894
Marwa MatboliMedicinal Biochemistry and Molecular Biology Department, Ain Shams University School of Medicine, Cairo 11566, Egypt.ORCID 0000-0002-6852-3954
Ain Shams University · EGBenha University · EGBaylor College of Medicine · USHelwan University · EGModern University for Information and Technology · EG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Nonalcoholic fatty liver disease (NAFLD) is one of the major seeds of liver cirrhosis and hepatocellular carcinoma. There is no convenient reliable non-invasive early diagnostic tool available for NAFLD/NASH diagnosis and stratification. Recently, the role of cytosolic sensor, stimulator of interferon genes (STING) signaling pathway in pathogenesis of nonalcoholic steatohepatitis (NASH) has been evidenced in research. We have selected

Indexed as

BiomarkersEndothelin-1FemaleHumansMaleMicroRNAsMitogen-Activated Protein Kinase 3Non-alcoholic Fatty Liver DiseaseRNA, Long NoncodingTumor Necrosis Factor-alphaBiomarkersEndothelin-1MAPK3 protein, humanMicroRNAsMitogen-Activated Protein Kinase 3RNA, Long NoncodingTumor Necrosis Factor-alphaNAFLDNASHRNARNAs panelsteatohepatitisTNF

Identifiers

PMID34828420
PMCPMC8619934
OpenAlexW3212191259

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.