Evidence map›Paper›PMID 34828527›Full record

ReviewHealthcare (Basel, Switzerland)2021

State of the Art in Hepatic Dysfunction in Pregnancy.

Valentin Nicolae Varlas, Roxana Bohîlțea, Gina Gheorghe, Georgiana Bostan, Gabriela Anca Angelescu, Ovidiu Nicolae Penes, Roxana Georgiana Bors, Eliza Cloțea, Nicolae Bacalbasa, Camelia Cristina Diaconu

Open access · goldAbstract readReview
In one paragraph

Review in Healthcare (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.6field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Article
  3. Bile Acids in Intrahepatic Cholestasis of Pregnancy.Diagnostics (Basel, Switzerland) · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Valentin Nicolae VarlasDepartment of Obstetrics and Gynecology, Filantropia Clinical Hospital, 011132 Bucharest, Romania.ORCID 0000-0002-8342-9819
Roxana BohîlțeaDepartment of Obstetrics and Gynecology, Filantropia Clinical Hospital, 011132 Bucharest, Romania.
Gina GheorgheDepartment of Internal Medicine, "Carol Davila" University of Medicine and Pharmacy, 050474 Bucharest, Romania.
Georgiana BostanDepartment of Obstetrics and Gynecology, County Emergency Hospital "St. John the New", 720034 Suceava, Romania.
Gabriela Anca Angelescu"Carol Davila" University of Medicine and Pharmacy, 020021 Bucharest, Romania.
Ovidiu Nicolae Penes"Carol Davila" University of Medicine and Pharmacy, 020021 Bucharest, Romania.ORCID 0000-0001-8123-0761
Roxana Georgiana BorsDepartment of Obstetrics and Gynecology, Filantropia Clinical Hospital, 011132 Bucharest, Romania.
Eliza CloțeaDepartment of Obstetrics and Gynecology, Filantropia Clinical Hospital, 011132 Bucharest, Romania.
Nicolae Bacalbasa"Carol Davila" University of Medicine and Pharmacy, 020021 Bucharest, Romania.
Camelia Cristina DiaconuDepartment of Internal Medicine, "Carol Davila" University of Medicine and Pharmacy, 050474 Bucharest, Romania.ORCID 0000-0001-6837-260X
Carol Davila University of Medicine and Pharmacy · ROClinical Emergency Hospital Bucharest · RO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hepatic dysfunction in pregnant women is always challenging for the obstetrician, as the spectrum of hepatic abnormalities can be very large and have various implications, both for mother and fetus. There is a diagnostic and therapeutic polymorphism of hepatic dysfunction in pregnancy and insufficient knowledge related to the etiopathogenesis and epidemiology of this disease. The clinical forms of hepatic dysfunction encountered in pregnancy can vary from liver diseases related to pregnancy (e.g., HELLP syndrome, intrahepatic cholestasis, hyperemesis gravidarum, or acute fatty liver of pregnancy) to de novo ones occurring in pregnancy, and pre-existing liver disease (cholelithiasis, Budd-Chiari syndrome, and cirrhosis). We performed a systematic literature search over 10 years. The review protocol assumed a search of two databases (PubMed

Indexed as

acute fatty liverBudd–Chiari syndromecholelithiasiscirrhosisHELLP syndromehyperemesis gravidarumintrahepatic cholestasisliver dysfunctionpregnancy

Identifiers

PMID34828527
PMCPMC8618725
OpenAlexW3210154254

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.