ArticleDiagnostics (Basel, Switzerland)2021
Atrial Fibrillation and Peri-Atrial Inflammation Measured through Adipose Tissue Attenuation on Cardiac Computed Tomography.
Article in Diagnostics (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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Who cites it
18 citing papers in PubMed, 26 citations in OpenAlex.
- Lifestyle modification in atrial fibrillation: Mechanisms, phenotypes and ablation outcomes.Experimental physiology · 2026Review
- Patients with persistent atrial fibrillation and metabolic comorbidities have an altered inflammatory state of atrial epicardial adipose tissue, which is linked to CT-attenuation.Cardiovascular diabetology · 2025Article
- Coronary Artery Inflammation and Epicardial Adipose Tissue Volume in Relation with Atrial Fibrillation Development.Diagnostics (Basel, Switzerland) · 2025Article
- Combined Brain-Cardiac CT in Ischemic Stroke: Unveiling Atrial Markers Linked to Large Vessel Occlusion in AF Patients.European journal of neurology · 2025Article
- Comparative Analysis of Perivascular Adipose Tissue Attenuation on Chest Computed Tomography Angiography in Patients with Marfan Syndrome: A Case-Control Study.Diagnostics (Basel, Switzerland) · 2025Article
- The association between features of epicardial adipose tissue and the risks of early recurrence after catheter ablation in patients with atrial fibrillation.Frontiers in cardiovascular medicine · 2025Article
- Epicardial fat density obtained with computed tomography imaging - more important than volume?Cardiovascular diabetology · 2024Review
- Coronary inflammation on chest computed tomography and COVID-19 mortality.European radiology · 2024Article
- Epicardial adipose tissue density predicts the presence of atrial fibrillation and its recurrence after catheter ablation: three-dimensional reconstructed image analysis.Heart and vessels · 2024Article
- Cardiovascular Disease from Pathophysiology to Risk Estimation: Is Inflammation Estimated through Perivascular Attenuation on Computed Tomography the Key?Life (Basel, Switzerland) · 2024Review
- Impact of pericoronary adipose tissue attenuation on recurrence after radiofrequency catheter ablation for atrial fibrillation.Clinical cardiology · 2023Article
- Discovery ofBiology · 2023Article
- The Role of Non-Invasive Multimodality Imaging in Chronic Coronary Syndrome: Anatomical and Functional Pathways.Diagnostics (Basel, Switzerland) · 2023Review
- Coronary Computed Tomography Angiography: Beyond Obstructive Coronary Artery Disease.Life (Basel, Switzerland) · 2023Review
- Incremental value of the combined brain-cardiac CT protocol on prediction of atrial fibrillation after stroke.European stroke journal · 2023Article
- Radiomic Phenotype of Periatrial Adipose Tissue in the Prognosis of Late Postablation Recurrence of Idiopathic Atrial Fibrillation.Sovremennye tekhnologii v meditsine · 2023Article
- Computed tomography measured epicardial adipose tissue and psoas muscle attenuation: new biomarkers to predict major adverse cardiac events (MACE) and mortality in patients with heart disease and critically ill patients. Part I: Epicardial adipose tissue.Anaesthesiology intensive therapy · 2023Article
- State of the art paper: Cardiac computed tomography of the left atrium in atrial fibrillation.Journal of cardiovascular computed tomographyReview
Corrections and comments
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundInflammation plays a key role in atrial fibrillation (AF). Epicardial adipose tissue around the atrial wall can influence atrial morpho-functional properties. The aim of this study was to assess whether an increased quantity and/or density of adipose tissue located around the left atrium (Fat-LA) are related to AF, independently from atrial size.
methodseighty patients who underwent AF ablation and 80 patients without history of AF were selected. The Fat-LA mass was quantified as tissue within -190 to -30 Hounsfield Units (HU) on cardiac computed tomography angiograms (CCTA), and the mean adipose tissue attenuation was assessed.
resultsAdipose tissue mass was higher in patients with AF (5.42 ± 2.94 mL) versus non-AF (4.16 ± 2.55 mL,
conclusionsFat-LA volume is significantly greater only in absolute terms in patients with AF, but this difference does not hold after adjusting for the larger LA of AF subjects. On the contrary, a higher Fat-LA density was associated with AF, independently from LA size, providing incremental value over other variables that are associated with AF.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.