Evidence map›Paper›PMID 34829514›Full record

GuidelineDiagnostics (Basel, Switzerland)2021

Best Practice Recommendations for the Implementation of a Digital Pathology Workflow in the Anatomic Pathology Laboratory by the European Society of Digital and Integrative Pathology (ESDIP).

Filippo Fraggetta, Vincenzo L'Imperio, David Ameisen, Rita Carvalho, Sabine Leh, Tim-Rasmus Kiehl, Mircea Serbanescu, Daniel Racoceanu, Vincenzo Della Mea, Antonio Polonia and 2 more

Abstract readGuideline
In one paragraph

Guideline in Diagnostics (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 66 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
66citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

66 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Guideline
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6 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Filippo FraggettaEuropean Society of Digital and Integrative Pathology (ESDIP), Rua da Constituição n°668, 1° Esq/Traseiras, 4200-194 Porto, Portugal.
Vincenzo L'ImperioEuropean Society of Digital and Integrative Pathology (ESDIP), Rua da Constituição n°668, 1° Esq/Traseiras, 4200-194 Porto, Portugal.ORCID 0000-0002-9284-2998
David AmeisenEuropean Society of Digital and Integrative Pathology (ESDIP), Rua da Constituição n°668, 1° Esq/Traseiras, 4200-194 Porto, Portugal.ORCID 0000-0001-9232-208X
Rita CarvalhoEuropean Society of Digital and Integrative Pathology (ESDIP), Rua da Constituição n°668, 1° Esq/Traseiras, 4200-194 Porto, Portugal.
Sabine LehEuropean Society of Digital and Integrative Pathology (ESDIP), Rua da Constituição n°668, 1° Esq/Traseiras, 4200-194 Porto, Portugal.ORCID 0000-0002-0764-2941
Tim-Rasmus KiehlEuropean Society of Digital and Integrative Pathology (ESDIP), Rua da Constituição n°668, 1° Esq/Traseiras, 4200-194 Porto, Portugal.ORCID 0000-0003-0616-7082
Mircea SerbanescuEuropean Society of Digital and Integrative Pathology (ESDIP), Rua da Constituição n°668, 1° Esq/Traseiras, 4200-194 Porto, Portugal.
Daniel RacoceanuEuropean Society of Digital and Integrative Pathology (ESDIP), Rua da Constituição n°668, 1° Esq/Traseiras, 4200-194 Porto, Portugal.ORCID 0000-0002-9416-1803
Vincenzo Della MeaEuropean Society of Digital and Integrative Pathology (ESDIP), Rua da Constituição n°668, 1° Esq/Traseiras, 4200-194 Porto, Portugal.ORCID 0000-0002-0144-3802
Antonio PoloniaEuropean Society of Digital and Integrative Pathology (ESDIP), Rua da Constituição n°668, 1° Esq/Traseiras, 4200-194 Porto, Portugal.ORCID 0000-0001-8312-1681
Norman ZerbeEuropean Society of Digital and Integrative Pathology (ESDIP), Rua da Constituição n°668, 1° Esq/Traseiras, 4200-194 Porto, Portugal.
Catarina EloyEuropean Society of Digital and Integrative Pathology (ESDIP), Rua da Constituição n°668, 1° Esq/Traseiras, 4200-194 Porto, Portugal.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The interest in implementing digital pathology (DP) workflows to obtain whole slide image (WSI) files for diagnostic purposes has increased in the last few years. The increasing performance of technical components and the Food and Drug Administration (FDA) approval of systems for primary diagnosis led to increased interest in applying DP workflows. However, despite this revolutionary transition, real world data suggest that a fully digital approach to the histological workflow has been implemented in only a minority of pathology laboratories. The objective of this study is to facilitate the implementation of DP workflows in pathology laboratories, helping those involved in this process of transformation to identify: (a) the scope and the boundaries of the DP transformation; (b) how to introduce automation to reduce errors; (c) how to introduce appropriate quality control to guarantee the safety of the process and (d) the hardware and software needed to implement DP systems inside the pathology laboratory. The European Society of Digital and Integrative Pathology (ESDIP) provided consensus-based recommendations developed through discussion among members of the Scientific Committee. The recommendations are thus based on the expertise of the panel members and on the agreement obtained after virtual meetings. Prior to publication, the recommendations were reviewed by members of the ESDIP Board. The recommendations comprehensively cover every step of the implementation of the digital workflow in the anatomic pathology department, emphasizing the importance of interoperability, automation and tracking of the entire process before the introduction of a scanning facility. Compared to the available national and international guidelines, the present document represents a practical, handy reference for the correct implementation of the digital workflow in Europe.

Indexed as

anatomic pathology workflowdigital pathologylaboratory information systemwhole slide imaging

Identifiers

PMID34829514
PMCPMC8623219

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.