Evidence map›Paper›PMID 34829837›Full record

ReviewBiomedicines2021

The Role of Ultrasound as a Diagnostic and Therapeutic Tool in Experimental Animal Models of Stroke: A Review.

Mari Carmen Gómez-de Frutos, Fernando Laso-García, Iván García-Suárez, Luke Diekhorst, Laura Otero-Ortega, María Alonso de Leciñana, Blanca Fuentes, Dolores Piniella, Gerardo Ruiz-Ares, Exuperio Díez-Tejedor and 1 more

Abstract readReview
In one paragraph

Review in Biomedicines, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Trial
  2. Article
  3. Commentary to Brain-wide continuous functional ultrasound imaging for real-time monitoring of hemodynamics during ischemic stroke.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2024
    Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Mari Carmen Gómez-de FrutosNeurological Sciences and Cerebrovascular Research Laboratory, Department of Neurology and Stroke Centre, La Paz University Hospital, Neuroscience Area of IdiPAZ Health Research Institute, Universidad Autónoma de Madrid, 28046 Madrid, Spain.
Fernando Laso-GarcíaNeurological Sciences and Cerebrovascular Research Laboratory, Department of Neurology and Stroke Centre, La Paz University Hospital, Neuroscience Area of IdiPAZ Health Research Institute, Universidad Autónoma de Madrid, 28046 Madrid, Spain.
Iván García-SuárezNeurological Sciences and Cerebrovascular Research Laboratory, Department of Neurology and Stroke Centre, La Paz University Hospital, Neuroscience Area of IdiPAZ Health Research Institute, Universidad Autónoma de Madrid, 28046 Madrid, Spain.
Luke DiekhorstNeurological Sciences and Cerebrovascular Research Laboratory, Department of Neurology and Stroke Centre, La Paz University Hospital, Neuroscience Area of IdiPAZ Health Research Institute, Universidad Autónoma de Madrid, 28046 Madrid, Spain.
Laura Otero-OrtegaNeurological Sciences and Cerebrovascular Research Laboratory, Department of Neurology and Stroke Centre, La Paz University Hospital, Neuroscience Area of IdiPAZ Health Research Institute, Universidad Autónoma de Madrid, 28046 Madrid, Spain.ORCID 0000-0001-8765-6341
María Alonso de LeciñanaNeurological Sciences and Cerebrovascular Research Laboratory, Department of Neurology and Stroke Centre, La Paz University Hospital, Neuroscience Area of IdiPAZ Health Research Institute, Universidad Autónoma de Madrid, 28046 Madrid, Spain.ORCID 0000-0002-4302-6580
Blanca FuentesNeurological Sciences and Cerebrovascular Research Laboratory, Department of Neurology and Stroke Centre, La Paz University Hospital, Neuroscience Area of IdiPAZ Health Research Institute, Universidad Autónoma de Madrid, 28046 Madrid, Spain.ORCID 0000-0002-0363-862X
Dolores PiniellaNeurological Sciences and Cerebrovascular Research Laboratory, Department of Neurology and Stroke Centre, La Paz University Hospital, Neuroscience Area of IdiPAZ Health Research Institute, Universidad Autónoma de Madrid, 28046 Madrid, Spain.
Gerardo Ruiz-AresNeurological Sciences and Cerebrovascular Research Laboratory, Department of Neurology and Stroke Centre, La Paz University Hospital, Neuroscience Area of IdiPAZ Health Research Institute, Universidad Autónoma de Madrid, 28046 Madrid, Spain.
Exuperio Díez-TejedorNeurological Sciences and Cerebrovascular Research Laboratory, Department of Neurology and Stroke Centre, La Paz University Hospital, Neuroscience Area of IdiPAZ Health Research Institute, Universidad Autónoma de Madrid, 28046 Madrid, Spain.
María Gutiérrez-FernándezNeurological Sciences and Cerebrovascular Research Laboratory, Department of Neurology and Stroke Centre, La Paz University Hospital, Neuroscience Area of IdiPAZ Health Research Institute, Universidad Autónoma de Madrid, 28046 Madrid, Spain.ORCID 0000-0002-6615-4729

Funding

European Regional Development Fund PI16/01052Instituto de Salud Carlos III CP15/00069Instituto de Salud Carlos III CP20/00024Instituto de Salud Carlos III CPII20/00002Instituto de Salud Carlos III FI17/00188Instituto de Salud Carlos III FI18/00026Instituto de Salud Carlos III PI16/01052Instituto de Salud Carlos III RD16/0019/0005
6 · The paper itself

Abstract

Ultrasound is a noninvasive technique that provides real-time imaging with excellent resolution, and several studies demonstrated the potential of ultrasound in acute ischemic stroke monitoring. However, only a few studies were performed using animal models, of which many showed ultrasound to be a safe and effective tool also in therapeutic applications. The full potential of ultrasound application in experimental stroke is yet to be explored to further determine the limitations of this technique and to ensure the accuracy of translational research. This review covers the current status of ultrasound applied to monitoring and treatment in experimental animal models of stroke and examines the safety, limitations, and future perspectives.

Indexed as

animal modelhemorrhagicischemicstrokeultrasound

Identifiers

PMID34829837
PMCPMC8615437

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.