Evidence map›Paper›PMID 34829898›Full record

ReviewBiomedicines2021

Plant-Derived Substances with Antibacterial, Antioxidant, and Flavoring Potential to Formulate Oral Health Care Products.

Marco A Lugo-Flores, Karen P Quintero-Cabello, Patricia Palafox-Rivera, Brenda A Silva-Espinoza, Manuel Reynaldo Cruz-Valenzuela, Luis Alberto Ortega-Ramirez, Gustavo Adolfo Gonzalez-Aguilar, Jesus Fernando Ayala-Zavala

Open access · goldAbstract readReview
In one paragraph

Review in Biomedicines, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
1.7field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it, 17 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Review
  4. Article
  5. Review
  6. Review
  7. Article
  8. Antibiotics (Basel, Switzerland) · 2023
    Article
  9. Article
  10. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Marco A Lugo-FloresCentro de Investigacion en Alimentacion y Desarrollo, A.C., Carretera Gustavo Enrique Astiazaran Rosas, No. 46, Col. La Victoria, Hermosillo C.P. 83304, Sonora, Mexico.
Karen P Quintero-CabelloCentro de Investigacion en Alimentacion y Desarrollo, A.C., Carretera Gustavo Enrique Astiazaran Rosas, No. 46, Col. La Victoria, Hermosillo C.P. 83304, Sonora, Mexico.
Patricia Palafox-RiveraCentro de Investigacion en Alimentacion y Desarrollo, A.C., Carretera Gustavo Enrique Astiazaran Rosas, No. 46, Col. La Victoria, Hermosillo C.P. 83304, Sonora, Mexico.
Brenda A Silva-EspinozaCentro de Investigacion en Alimentacion y Desarrollo, A.C., Carretera Gustavo Enrique Astiazaran Rosas, No. 46, Col. La Victoria, Hermosillo C.P. 83304, Sonora, Mexico.
Manuel Reynaldo Cruz-ValenzuelaCentro de Investigacion en Alimentacion y Desarrollo, A.C., Carretera Gustavo Enrique Astiazaran Rosas, No. 46, Col. La Victoria, Hermosillo C.P. 83304, Sonora, Mexico.ORCID 0000-0002-3602-2928
Luis Alberto Ortega-RamirezUnidad Académica San Luis Río Colorado, Universidad Estatal de Sonora, Carretera, Sonoyta-San Luis Río Colorado km. 6.5, Parque Industrial, San Luis Río Colorado C.P. 83500, Sonora, Mexico.
Gustavo Adolfo Gonzalez-AguilarCentro de Investigacion en Alimentacion y Desarrollo, A.C., Carretera Gustavo Enrique Astiazaran Rosas, No. 46, Col. La Victoria, Hermosillo C.P. 83304, Sonora, Mexico.ORCID 0000-0002-7452-286X
Jesus Fernando Ayala-ZavalaCentro de Investigacion en Alimentacion y Desarrollo, A.C., Carretera Gustavo Enrique Astiazaran Rosas, No. 46, Col. La Victoria, Hermosillo C.P. 83304, Sonora, Mexico.ORCID 0000-0002-0691-6453
Centro de Investigación en Alimentación y Desarrollo · MXUniversidad de Sonora · MX

Funding

Consejo Nacional de Ciencia y Tecnología CB-2013-01-222691
6 · The paper itself

Abstract

Bacterial diseases and reactive oxygen species can cause dental caries and oral cancer. Therefore, the present review analyzes and discusses the antibacterial and antioxidant properties of synthetic and plant-derived substances and their current and future patents to formulate dental products. The reviewed evidence indicates that chlorhexidine, fluorides, and hydrogen peroxide have adverse effects on the sensory acceptability of oral care products. As an alternative, plant-derived substances have antimicrobial and antioxidant properties that can be used in their formulation. Also, adding plant metabolites favors the sensory acceptability of dental products compared with synthetic compounds. Therefore, plant-derived substances have antibacterial, antioxidant, and flavoring activity with the potential to be used in the formulation of toothpaste, mouth rinses, dentures cleansers-fixatives, and saliva substitutes.

Indexed as

bacterial biofilmfree radicalsoral microbiotaplant extractsynergism

Identifiers

PMID34829898
PMCPMC8615420
OpenAlexW3212648594

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.