Evidence map›Paper›PMID 34830567›Full record

ArticleJournal of clinical medicine2021

Cardiac Surgery Associated AKI Prevention Strategies and Medical Treatment for CSA-AKI.

Marlies Ostermann, Gudrun Kunst, Eleanor Baker, Kittisak Weerapolchai, Nuttha Lumlertgul

Abstract read
In one paragraph

Article in Journal of clinical medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 3 syntheses or guidelines pooled it.

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  15. Kidney Injury Following Cardiac Surgery: A Review of Our Current Understanding.American journal of cardiovascular drugs : drugs, devices, and other interventions · 2025
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Marlies OstermannDepartment of Critical Care, King's College London, Guy's & St Thomas' NHS Foundation Trust, London SE1 7EH, UK.ORCID 0000-0001-9500-9080
Gudrun KunstDepartment of Anaesthesia, School of Cardiovascular Medicine & Sciences, King's College Hospital, King's College London, London SE5 9RS, UK.
Eleanor BakerDepartment of Critical Care, King's College London, Guy's & St Thomas' NHS Foundation Trust, London SE1 7EH, UK.
Kittisak WeerapolchaiDivision of Urology, Department of Surgery, Somdech Phra Pinklao Hospital, Bangkok 10330, Thailand.
Nuttha LumlertgulDepartment of Critical Care, King's College London, Guy's & St Thomas' NHS Foundation Trust, London SE1 7EH, UK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Acute kidney injury (AKI) is common after cardiac surgery. To date, there are no specific pharmacological therapies. In this review, we summarise the existing evidence for prevention and management of cardiac surgery-associated AKI and outline areas for future research. Preoperatively, angiotensin-converting enzyme inhibitors and angiotensin receptor blockers should be withheld and nephrotoxins should be avoided to reduce the risk. Intraoperative strategies include goal-directed therapy with individualised blood pressure management and administration of balanced fluids, the use of circuits with biocompatible coatings, application of minimally invasive extracorporeal circulation, and lung protective ventilation. Postoperative management should be in accordance with current KDIGO AKI recommendations.

Indexed as

acute kidney injury (AKI)cardiac surgerycardiac surgery associated AKIcardiovascularmanagementpreventionrenal

Identifiers

PMID34830567
PMCPMC8618011

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.