Evidence map›Paper›PMID 34830910›Full record

ArticleCancers2021

Prognostic Matrisomal Gene Panel and Its Association with Immune Cell Infiltration in Head and Neck Carcinomas.

Yuri Belotti, Su Bin Lim, Narayanan Gopalakrishna Iyer, Wan-Teck Lim, Chwee Teck Lim

Open access · goldAbstract read
In one paragraph

Article in Cancers, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.5field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 8 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 3 countries.

Yuri BelottiInstitute for Health Innovation and Technology, National University of Singapore, 14 Medical Drive, Singapore 117599, Singapore.ORCID 0000-0001-6153-7096
Su Bin LimDepartment of Biochemistry and Molecular Biology, Ajou University School of Medicine, Suwon 16499, Korea.ORCID 0000-0003-1752-7039
Narayanan Gopalakrishna IyerDepartment of Head and Neck Surgery, National Cancer Centre Singapore, 11 Hospital Drive, Singapore 169610, Singapore.ORCID 0000-0002-8812-6219
Wan-Teck LimDuke-NUS Medical School, 8 College Road, Singapore 169857, Singapore.ORCID 0000-0002-4655-0206
Chwee Teck LimInstitute for Health Innovation and Technology, National University of Singapore, 14 Medical Drive, Singapore 117599, Singapore.ORCID 0000-0003-4019-9782
National University of Singapore · SGAgency for Science, Technology and Research · SGAjou University · KRDuke-NUS Medical School · SG

Funding

Ajou University School of Medicine new faculty research fundInstitute for Health Innovation & Technology R-722-000-003-750National Medical Research Council NMRC/CSA/001/2016National Medical Research Council NMRC/CSA-INV/0025/2017National Research Foundation of Korea NRF/MSIT 2021R1F1A1064122NCC Cancer Fund
6 · The paper itself

Abstract

Squamous cell carcinoma of the head and neck (SCCHN) is common worldwide and related to several risk factors including smoking, alcohol consumption, poor dentition and human papillomavirus (HPV) infection. Different etiological factors may influence the tumor microenvironment and play a role in dictating response to therapeutics. Here, we sought to investigate whether an early-stage SCCHN-specific prognostic matrisome-derived gene signature could be identified for HPV-negative SCCHN patients (

Indexed as

bioinformaticsextracellular matrixhead and neck cancerHPVprognostic biomarkerTCGA

Identifiers

PMID34830910
PMCPMC8616409
OpenAlexW3213159860

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.