Evidence map›Paper›PMID 34831137›Full record

ReviewCells2021

Two-Pore-Domain Potassium (K

Felix Wiedmann, Norbert Frey, Constanze Schmidt

Abstract readReview
In one paragraph

Review in Cells, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. KPharmaceuticals (Basel, Switzerland) · 2026
    Review
  5. Mechanosensitive ion channels as novel targets in osteoporosis.Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research · 2026
    Review
  6. Cardiac Manifestations ofHealth science reports · 2026
    Review
  7. Article
  8. Structure-Function Relationships of KAdvances in experimental medicine and biology · 2026
    Review
  9. Review
  10. Review
  11. Article
  12. Review
  13. Disease mechanism and novel drug therapies for atrial fibrillation.Medizinische Genetik : Mitteilungsblatt des Berufsverbandes Medizinische Genetik e.V · 2025
    Article
  14. Andrology · 2025
    Review
  15. Article
  16. Article
  17. The effects of doxapram and its potential interactions with K2P channels in experimental model preparations.Journal of comparative physiology. A, Neuroethology, sensory, neural, and behavioral physiology · 2024
    Article
  18. SARS-CoV-2 ORF 3a-mediated currents are inhibited by antiarrhythmic drugs.Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology · 2024
    Article
  19. Article
  20. Evolution of two-pore domain potassium channels and their gene expression in zebrafish embryos.Developmental dynamics : an official publication of the American Association of Anatomists · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Felix WiedmannDepartment of Cardiology, University of Heidelberg, 69120 Heidelberg, Germany.ORCID 0000-0001-8168-0025
Norbert FreyDepartment of Cardiology, University of Heidelberg, 69120 Heidelberg, Germany.
Constanze SchmidtDepartment of Cardiology, University of Heidelberg, 69120 Heidelberg, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Two-pore-domain potassium (K

Indexed as

Atrial RemodelingAnimalsCardiovascular DiseasesGene Expression RegulationHumansMyocardiumPotassium Channels, Tandem Pore DomainPotassium Channels, Tandem Pore DomainK2P-channelTASK-1TREK-1two-pore-domain potassium channel

Identifiers

PMID34831137
PMCPMC8616229

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.