Evidence mapPaperPMID 34835964Full record

ReviewNutrients2021

Pediatric Obesity-Related Asthma: The Role of Nutrition and Nutrients in Prevention and Treatment.

Valeria Calcaterra, Elvira Verduci, Michele Ghezzi, Hellas Cena, Martina Chiara Pascuzzi, Corrado Regalbuto, Rossella Lamberti, Virginia Rossi, Matteo Manuelli, Alessandra Bosetti and 1 more

Open access · goldAbstract readReview
In one paragraph

Review in Nutrients, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
2.6field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 33 citations in OpenAlex.

  1. Metabolic Reprogramming and ILC2 Plasticity in Obesity-related Asthma.Clinical reviews in allergy & immunology · 2026
    Review
  2. Early childhood asthma and adiposity until adolescence: A prospective birth cohort study using body fat percentage.Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology · 2026
    Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Review
  9. Article
  10. Review
  11. Importance of diet in children and adolescents with obesity and asthma.Pediatric endocrinology, diabetes, and metabolism · 2024
    Review
  12. Article
  13. Review
  14. Review
  15. Review
  16. An Overview of the Obese-Asthma Phenotype in Children.International journal of environmental research and public health · 2022
    Review
  17. Review
  18. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 1 country.

Valeria CalcaterraPediatric and Adolescent Unit, Department of Internal Medicine, University of Pavia, 27100 Pavia, Italy.ORCID 0000-0002-2137-5974
Elvira VerduciPediatric Department, "Vittore Buzzi" Children's Hospital, 20154 Milan, Italy.ORCID 0000-0003-2111-3111
Michele GhezziPediatric Department, "Vittore Buzzi" Children's Hospital, 20154 Milan, Italy.ORCID 0000-0002-7434-9112
Hellas CenaLaboratory of Dietetics and Clinical Nutrition, Department of Public Health, Experimental and Forensic Medicine, University of Pavia, 27100 Pavia, Italy.ORCID 0000-0002-5752-6199
Martina Chiara PascuzziPediatric Department, "Vittore Buzzi" Children's Hospital, 20154 Milan, Italy.ORCID 0000-0003-3549-498X
Corrado RegalbutoPediatric Unit, Department of Maternal and Children's Health, Fondazione IRCCS Policlinico S. Matteo and University of Pavia, 27100 Pavia, Italy.
Rossella LambertiPediatric Department, "Vittore Buzzi" Children's Hospital, 20154 Milan, Italy.
Virginia RossiPediatric Department, "Vittore Buzzi" Children's Hospital, 20154 Milan, Italy.ORCID 0000-0001-8363-9210
Matteo ManuelliClinical Nutrition and Dietetics Service, Unit of Internal Medicine and Endocrinology, ICS Maugeri IRCCS, 27100 Pavia, Italy.
Alessandra BosettiPediatric Department, "Vittore Buzzi" Children's Hospital, 20154 Milan, Italy.
Gian Vincenzo ZuccottiPediatric Department, "Vittore Buzzi" Children's Hospital, 20154 Milan, Italy.ORCID 0000-0002-2795-9874
Ospedale dei Bambini Vittore Buzzi · ITUniversity of Pavia · ITUniversity of Milan · ITIstituti Clinici Scientifici Maugeri · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Childhood obesity rates have dramatically risen in numerous countries worldwide. Obesity is likely a factor in increased asthma risk, which is already one of the most widespread chronic respiratory pathologies. The pathogenic mechanism of asthma risk has still not yet been fully elucidated. Moreover, the role of obesity-related inflammation and pulmonary overreaction to environmental triggers, which ultimately result in asthma-like symptoms, and the importance of dietary characteristics is well recognized. Diet is an important adjustable element in the asthma development. Food-specific composition of the diet, in particular fat, sugar, and low-quality nutrients, is likely to promote the chronic inflammatory state seen in asthmatic patients with obesity. An unbalanced diet or supplementation as a way to control asthma more efficiently has been described. A personalized dietary intervention may improve respiratory symptoms and signs and therapeutic response. In this narrative review, we presented and discussed more recent literature on asthma associated with obesity among children, focusing on the risk of asthma among children with obesity, asthma as a result of obesity focusing on the role of adipose tissue as a mediator of systemic and local airway inflammation implicated in asthma regulation, and the impact of nutrition and nutrients in the development and treatment of asthma. Appropriate early nutritional intervention could possibly be critical in preventing and managing asthma associated with obesity among children.

Indexed as

NutrientsNutritional StatusAsthmaHumansInflammationLungPediatric ObesityNutrientsasthmachildrendietnutrientsnutritionobesitypediatrics

Identifiers

PMID34835964
PMCPMC8620690
OpenAlexW3208495646

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.