Evidence map›Paper›PMID 34836047›Full record

ArticleNutrients2021

The Role of 20-HETE, COX, Thromboxane Receptors, and Blood Plasma Antioxidant Status in Vascular Relaxation of Copper-Nanoparticle-Fed WKY Rats.

Michał Majewski, Jerzy Juśkiewicz, Magdalena Krajewska-Włodarczyk, Leszek Gromadziński, Katarzyna Socha, Ewelina Cholewińska, Katarzyna Ognik

Abstract read
In one paragraph

Article in Nutrients, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. The interactions of copper, glutamate, and cuproptosis: insights into brain health and Alzheimer's disease pathology.Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Michał MajewskiDepartment of Pharmacology and Toxicology, UWM, 10-082 Olsztyn, Poland.ORCID 0000-0001-6304-0673
Jerzy JuśkiewiczDivision of Food Science, Institute of Animal Reproduction and Food Research, Polish Academy of Sciences, 10-748 Olsztyn, Poland.ORCID 0000-0003-0068-5970
Magdalena Krajewska-WłodarczykDepartment of Mental and Psychosomatic Diseases, Faculty of Medicine, UWM, 10-228 Olsztyn, Poland.ORCID 0000-0002-7857-347X
Leszek GromadzińskiDepartment of Cardiology and Internal Medicine, Faculty of Medicine, UWM, 10-082 Olsztyn, Poland.ORCID 0000-0002-8827-4203
Katarzyna SochaDepartment of Bromatology, Medical University of Białystok, 15-222 Białystok, Poland.ORCID 0000-0002-5949-7061
Ewelina CholewińskaDepartment of Biochemistry and Toxicology, Faculty of Biology, Animal Sciences and Bioeconomy, University of Life Sciences, 20-950 Lublin, Poland.ORCID 0000-0003-0437-4766
Katarzyna OgnikDepartment of Biochemistry and Toxicology, Faculty of Biology, Animal Sciences and Bioeconomy, University of Life Sciences, 20-950 Lublin, Poland.ORCID 0000-0003-4393-4092

Funding

National Science Center 2019/03/X/NZ9/00171
6 · The paper itself

Abstract

Recently, the addition of copper nanoparticles (NPs) in a daily diet (6.5 mg/kg) was studied in different animal models as a possible alternative to ionic forms. Male Wistar-Kyoto rats (24-week-old,

Indexed as

Dietary SupplementsAnimalsAntioxidantsAorta, ThoracicCopperEndothelium, VascularHydroxyeicosatetraenoic AcidsMaleMetal NanoparticlesModels, AnimalProstaglandin-Endoperoxide SynthasesRatsRats, Inbred WKYReceptors, ThromboxaneVasoconstrictionVasodilation20-hydroxy-5,8,11,14-eicosatetraenoic acidAntioxidantsCopperHydroxyeicosatetraenoic AcidsProstaglandin-Endoperoxide SynthasesReceptors, ThromboxaneVasodilator Agents20-HETEagingfuregrelateHET0016indomethacinNS-398SQ-29,548thromboxane-A2

Identifiers

PMID34836047
PMCPMC8623823

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.