Evidence map›Paper›PMID 34836049›Full record

ArticleNutrients2021

Maternal Diet, Infection, and Risk of Cord Blood Inflammation in the Bangladesh Projahnmo Pregnancy Cohort.

Anne Cc Lee, Sara Cherkerzian, Ingrid E Olson, Salahuddin Ahmed, Nabidul Haque Chowdhury, Rasheda Khanam, Sayedur Rahman, Chloe Andrews, Abdullah H Baqui, Wafaie Fawzi and 6 more

Open access · goldAbstract read
In one paragraph

Article in Nutrients, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.7field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 7 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 5 institutions in 2 countries.

Anne Cc LeeDepartment of Pediatric Newborn Medicine, Brigham and Women's Hospital, Boston, MA 02115, USA.
Sara CherkerzianDepartment of Pediatric Newborn Medicine, Brigham and Women's Hospital, Boston, MA 02115, USA.
Ingrid E OlsonDepartment of Pediatric Newborn Medicine, Brigham and Women's Hospital, Boston, MA 02115, USA.
Salahuddin AhmedProjahnmo Research Foundation, Banani, Dhaka 1213, Bangladesh.ORCID 0000-0001-6771-0638
Nabidul Haque ChowdhuryProjahnmo Research Foundation, Banani, Dhaka 1213, Bangladesh.ORCID 0000-0002-6149-1152
Rasheda KhanamJohns Hopkins Bloomberg School of Public Health, Baltimore, MD 21205, USA.
Sayedur RahmanProjahnmo Research Foundation, Banani, Dhaka 1213, Bangladesh.
Chloe AndrewsDepartment of Pediatric Newborn Medicine, Brigham and Women's Hospital, Boston, MA 02115, USA.
Abdullah H BaquiJohns Hopkins Bloomberg School of Public Health, Baltimore, MD 21205, USA.
Wafaie FawziHarvard T.H. Chan School of Public Health, Boston, MA 02115, USA.
Terrie E InderDepartment of Pediatric Newborn Medicine, Brigham and Women's Hospital, Boston, MA 02115, USA.
Stephanie NarteyDepartment of Obstetrics, Gynecology and Reproductive Biology, Brigham and Women's Hospital, Boston, MA 02115, USA.
Charles A NelsonHarvard Medical School, Boston, MA 02115, USA.
Emily OkenHarvard Medical School, Boston, MA 02115, USA.
Sarbattama SenDepartment of Pediatric Newborn Medicine, Brigham and Women's Hospital, Boston, MA 02115, USA.
Raina FichorovaHarvard Medical School, Boston, MA 02115, USA.
Brigham and Women's Hospital · USBiomedical Research Foundation · BDHarvard University · USJohns Hopkins University · USBoston Children's Hospital · US

Funding

Genetic Analysis and Manipulation Core (GAEC)P50HD105351 · NICHD · BOSTON CHILDREN'S HOSPITAL · PI Hisashi Umemori · 2021 to 2026
$9.4M
The Roles of Perinatal Nutrition, Infection and Inflammation in the Neurodevelopment of Bangladeshi InfantsK23HD091390 · NICHD · BRIGHAM AND WOMEN'S HOSPITAL · PI LEE, ANNE SHEE CC · 2017 to 2021
$864k
NICHD NIH HHS K23 HD091390NICHD NIH HHS P50 HD105351
6 · The paper itself

Abstract

Inflammation may adversely affect early human brain development. We aimed to assess the role of maternal nutrition and infections on cord blood inflammation. In a pregnancy cohort in Sylhet, Bangladesh, we enrolled 251 consecutive pregnancies resulting in a term livebirth from July 2016-March 2017. Stillbirths, preterm births, and cases of neonatal encephalopathy were excluded. We prospectively collected data on maternal diet (food frequency questionnaire) and morbidity, and analyzed umbilical cord blood for interleukin (IL)-1α, IL-1β, IL-6, IL-8 and C-reactive protein. We determined associations between nutrition and infection exposures and cord cytokine elevation (≥75% vs. <75%) using logistic regression, adjusting for confounders. One-third of mothers were underweight (BMI < 18.5 kg/m

Indexed as

Maternal Nutritional Physiological PhenomenaAdultBangladeshC-Reactive ProteinDietDiet SurveysFemaleFetal BloodFetal DevelopmentHumansInfant, NewbornInflammationInterleukinsLogistic ModelsNutritional StatusPregnancyC-Reactive ProteinInterleukinsinflammationmicronutrientprenatal infectionundernutrition

Identifiers

PMID34836049
PMCPMC8623045
OpenAlexW3208011182

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.