Evidence map›Paper›PMID 34836055›Full record

ReviewNutrients2021

Natural Products for Pancreatic Cancer Treatment: From Traditional Medicine to Modern Drug Discovery.

Ahyeon Kim, Jiwon Ha, Jeongeun Kim, Yongmin Cho, Jimyung Ahn, Chunhoo Cheon, Sung-Hoon Kim, Seong-Gyu Ko, Bonglee Kim

Open access · goldAbstract readReview
In one paragraph

Review in Nutrients, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers.

0numbers the graph read from it
0cells of the map it votes in
35citing papers in PubMed
10.2field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

35 citing papers in PubMed, 53 citations in OpenAlex.

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  18. Systemic treatment for advanced pancreatic cancer.World journal of gastrointestinal oncology · 2023
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Ahyeon KimCollege of Korean Medicine, Kyung Hee University, Seoul 02447, Korea.
Jiwon HaCollege of Korean Medicine, Kyung Hee University, Seoul 02447, Korea.
Jeongeun KimCollege of Korean Medicine, Kyung Hee University, Seoul 02447, Korea.
Yongmin ChoDepartment of Pathology, College of Korean Medicine, Kyung Hee University, Seoul 02447, Korea.
Jimyung AhnDepartment of Pathology, College of Korean Medicine, Kyung Hee University, Seoul 02447, Korea.
Chunhoo CheonKorean Medicine-Based Drug Repositioning Cancer Research Center, College of Korean Medicine, Kyung Hee University, Seoul 02447, Korea.
Sung-Hoon KimDepartment of Pathology, College of Korean Medicine, Kyung Hee University, Seoul 02447, Korea.ORCID 0000-0003-2423-1973
Seong-Gyu KoKorean Medicine-Based Drug Repositioning Cancer Research Center, College of Korean Medicine, Kyung Hee University, Seoul 02447, Korea.ORCID 0000-0002-2345-430X
Bonglee KimCollege of Korean Medicine, Kyung Hee University, Seoul 02447, Korea.ORCID 0000-0002-8678-156X
Kyung Hee University · KR

Funding

a grant of the Korea Health 875 Technology R&D Project through the Korea Health Industry Development Institute (KHIDI), 876 funded by the Ministry of Health & Welfare, Republic of Korea HF20C0038a grant of the Korea Health Technology R&D Project 873 through the Korea Health Industry Development Institute (KHIDI), funded by the Ministry of 874 Health & Welfare, Republic of Korea HF20C0116Basic Science Research Program through the National 870 Research Foundation of Korea (NRF) funded by the Ministry of Education NRF-871 2020R1I1A2066868the National Research Foundation of Korea (NRF) grant funded by the Korea 872 government (MSIT) No. 2020R1A5A2019413
6 · The paper itself

Abstract

Pancreatic cancer, the seventh most lethal cancer around the world, is considered complicated cancer due to poor prognosis and difficulty in treatment. Despite all the conventional treatments, including surgical therapy and chemotherapy, the mortality rate is still high. Therefore, the possibility of using natural products for pancreatic cancer is increasing. In this study, 68 natural products that have anti-pancreatic cancer effects reported within five years were reviewed. The mechanisms of anti-cancer effects were divided into four types: apoptosis, anti-metastasis, anti-angiogenesis, and anti-resistance. Most of the studies were conducted for natural products that induce apoptosis in pancreatic cancer. Among them, plant extracts such as

Indexed as

Angiogenesis InhibitorsAntineoplastic Agents, PhytogenicApoptosisBiological ProductsDrug DiscoveryDrug Resistance, NeoplasmHumansMedicine, TraditionalPancreatic NeoplasmsPhytotherapyPlant ExtractsAngiogenesis InhibitorsAntineoplastic Agents, PhytogenicBiological ProductsPlant Extractsangiogenesisapoptosisdrug resistancemetastasisnatural productpancreatic cancertraditional medicine

Identifiers

PMID34836055
PMCPMC8625071
OpenAlexW3208101093

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.