ArticleNutrients2021
Consumption of Non-Nutritive Sweetener, Acesulfame Potassium Exacerbates Atherosclerosis through Dysregulation of Lipid Metabolism in ApoE
Article in Nutrients, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
10 citing papers in PubMed, 2 syntheses or guidelines pooled it, 25 citations in OpenAlex.
- Impact of Artificial Sweeteners on Inflammation Markers: A Systematic Review of Animal Studies.Nutrients · 2025Pooled it
- The effects of non-nutritive sweeteners on lipid profile in adults: a systematic review and meta-analysis of randomized controlled clinical trials.Scientific reports · 2025Pooled it
- Urinary Sweeteners and Sugars in Relation to Childhood Obesity: The SWEET Project.The Journal of nutrition · 2025Article
- Potential Effects of Low-Calorie Sweeteners on Human Health.Nutrients · 2025Review
- Re-evaluation of acesulfame K (E 950) as food additive.EFSA journal. European Food Safety Authority · 2025Article
- Intake of Artificial Sweeteners through Soft Drinks in the Preschool- and School-Aged Population.Nutrients · 2024Article
- Classification of Food Additives Using UV Spectroscopy and One-Dimensional Convolutional Neural Network.Sensors (Basel, Switzerland) · 2023Article
- Long-Term Consumption of Sucralose Induces Hepatic Insulin Resistance through an Extracellular Signal-Regulated Kinase 1/2-Dependent Pathway.Nutrients · 2023Article
- Interactions of Non-Nutritive Artificial Sweeteners with the Microbiome in Metabolic Syndrome.Immunometabolism · 2022Article
- Deciphering the combination mechanisms of Gualou-Xiebai herb pair against atherosclerosis by network pharmacology and HPLC-Q-TOF-MS technology.Frontiers in pharmacology · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 5 institutions in 1 country.
Funding
Abstract
Obesity is associated with the risk of cardiovascular disease, and non-nutritive sweetener, such as acesulfame potassium (AceK) has been used to combat obesity. However, the effects of AceK on cardiovascular disease are still unclear. In this study, high cholesterol diet (HCD)-fed ApoE
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.