Evidence map›Paper›PMID 34836254›Full record

ReviewNutrients2021

Impact of Exercise on Gut Microbiota in Obesity.

Jerónimo Aragón-Vela, Patricio Solis-Urra, Francisco Javier Ruiz-Ojeda, Ana Isabel Álvarez-Mercado, Jorge Olivares-Arancibia, Julio Plaza-Diaz

Open access · goldAbstract readReview
In one paragraph

Review in Nutrients, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 52 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
52citing papers in PubMed, 3 pooled it
4.2field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

52 citing papers in PubMed, 3 syntheses or guidelines pooled it, 77 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Effect of Intensity and Duration of Exercise on Gut Microbiota in Humans: A Systematic Review.International journal of environmental research and public health · 2022
    Pooled it
  4. Trial
  5. Article
  6. Article
  7. Review
  8. Review
  9. Review
  10. Article
  11. Article
  12. Article
  13. Article
  14. Review
  15. Article
  16. Review
  17. Aerobic exercise regulates gut microbiota profiles and metabolite in the early stage of Alzheimer's disease.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2025
    Article
  18. Exosomes and microRNAs as mediators of the exercise.European journal of medical research · 2025
    Review
  19. Article
  20. Dietary low levels ofFrontiers in microbiology · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 4 countries.

Jerónimo Aragón-VelaDepartment of Physiology, School of Pharmacy, University of Granada, Campus de Cartuja s/n, 18071 Granada, Spain.ORCID 0000-0002-2550-6695
Patricio Solis-UrraPROFITH "PROmoting FITness and Health through Physical Activity" Research Group, Department of Physical Education and Sports, Faculty of Sports Science, University of Granada, 18071 Granada, Spain.ORCID 0000-0002-2493-9528
Francisco Javier Ruiz-OjedaInstitute of Nutrition and Food Technology "José Mataix", Center of Biomedical Research, University of Granada, Avda. del Conocimiento s/n, 18016 Granada, Spain.
Ana Isabel Álvarez-MercadoInstitute of Nutrition and Food Technology "José Mataix", Center of Biomedical Research, University of Granada, Avda. del Conocimiento s/n, 18016 Granada, Spain.ORCID 0000-0002-8476-9970
Jorge Olivares-ArancibiaGrupo AFySE, Investigación en Actividad Física y Salud Escolar, Escuela de Pedagogía en Educación Física, Facultad de Educación, Universidad de las Américas, Santiago 8370035, Chile.ORCID 0000-0002-7186-3941
Julio Plaza-DiazDepartment of Biochemistry and Molecular Biology II, School of Pharmacy, University of Granada, 18071 Granada, Spain.ORCID 0000-0002-5171-9408
Universidad de Granada · ESPontificia Universidad Católica de Valparaíso · CLUniversidad Andrés Bello · CL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Physical activity, exercise, or physical fitness are being studied as helpful nonpharmacological therapies to reduce signaling pathways related to inflammation. Studies describing changes in intestinal microbiota have stated that physical activity could increase the microbial variance and enhance the ratio of Firmicutes/Bacteroidetes, and both actions could neutralize the obesity progression and diminish body weight. The aim of this review is to provide an overview of the literature describing the relationship between physical activity profiles and gut microbiota and in obesity and some associated comorbidities. Promoting physical activity could support as a treatment to maintain the gut microbiota composition or to restore the balance toward an improvement of dysbiosis in obesity; however, these mechanisms need to be studied in more detail. The opportunity to control the microbiota by physical activity to improve health results and decrease obesity and related comorbidities is very attractive. Nevertheless, several incompletely answered questions need to be addressed before this strategy can be implemented.

Indexed as

ExerciseGastrointestinal MicrobiomeObesityBacillotaBacteroidetesBody WeightDysbiosisHumansInflammationNoncommunicable Diseaseschildrengut microbiotahealthhumansnon-communicable diseasesobesityphysical activity

Identifiers

PMID34836254
PMCPMC8624603
OpenAlexW3211894860

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.