Evidence map›Paper›PMID 34844950›Full record

ArticleJournal of clinical pathology2023

Determining common variants in patients with haemophilia A in South Vietnam and screening female carriers in their family members.

Bang Suong Thi Nguyen, Xuan Thao Thi Le, Nghia Huynh, Huy Huu Nguyen, Cong-Minh Truong Nguyen, Bac Hoang Nguyen

Open access · hybridAbstract read
In one paragraph

Article in Journal of clinical pathology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.3field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 2 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Bang Suong Thi NguyenHo Chi Minh City University of Medicine and Pharmacy, Ho Chi Minh City, Vietnam.
Xuan Thao Thi LeHo Chi Minh City University of Medicine and Pharmacy, Ho Chi Minh City, Vietnam.
Nghia HuynhHo Chi Minh City University of Medicine and Pharmacy, Ho Chi Minh City, Vietnam.
Huy Huu NguyenLaboratory Department, Ho Chi Minh City University of Medicine and Pharmacy, Ho Chi Minh City University Medical Center, Ho Chi Minh City, Vietnam.
Cong-Minh Truong NguyenHo Chi Minh City University of Medicine and Pharmacy, Ho Chi Minh City, Vietnam.
Bac Hoang NguyenHo Chi Minh City University of Medicine and Pharmacy, Ho Chi Minh City, Vietnam xuanthao.le@gmail.com.ORCID http://orcid.org/0000-0003-2802-9510
University of Medicine and Pharmacy at Ho Chi Minh City · VN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimsThe aim of this study was to determine common variants in

methodsGenetic analysis was conducted in 71 patients who were clinically diagnosed with HA and 152 related female members in South Vietnam by a combination of inversion PCR (I-PCR), multiplex PCR and direct sequencing.

resultsVariants in

conclusionsThese findings were the first to provide important information about the presence of Inv22 and point mutation in Vietnamese patients with HA, the mothers and their female family members. It demonstrated that genetic diagnosis and counselling for HA carriers were essential factors for future improvements in comprehensive and equitable healthcare polices for patients with HA and FCs in Vietnam.

Indexed as

Hemophilia AChromosome InversionFactor VIIIFamilyFemaleHumansMultiplex Polymerase Chain ReactionMutationVietnamFactor VIIIbiochemistrygeneticshemophilia A

Identifiers

PMID34844950
PMCPMC10176336
OpenAlexW3215255486

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.