Evidence map›Paper›PMID 34846691›Full record

SynthesisNeuroinformatics2022

ENIGMA + COINSTAC: Improving Findability, Accessibility, Interoperability, and Re-usability.

Jessica A Turner, Vince D Calhoun, Paul M Thompson, Neda Jahanshad, Christopher R K Ching, Sophia I Thomopoulos, Eric Verner, Gregory P Strauss, Anthony O Ahmed, Matthew D Turner and 8 more

Open access · hybridAbstract readMeta-Analysis
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in Neuroinformatics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.9field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Current best practices and future opportunities for reproducible findings using large-scale neuroimaging in psychiatry.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2024
    Review
  3. Article
  4. Article
  5. Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors at 10 institutions in 1 country.

Jessica A TurnerPsychology Department, Georgia State University, Atlanta, GA, USA. jturner63@gsu.edu.ORCID http://orcid.org/0000-0003-0076-8434
Vince D CalhounPsychology Department, Georgia State University, Atlanta, GA, USA.ORCID http://orcid.org/0000-0001-9058-0747
Paul M ThompsonImaging Genetics Center, Mark & Mary Stevens Neuroimaging and Informatics Institute, Keck School of Medicine, University of Southern California, Marina del Rey, CA, USA.ORCID http://orcid.org/0000-0002-4720-8867
Neda JahanshadImaging Genetics Center, Mark & Mary Stevens Neuroimaging and Informatics Institute, Keck School of Medicine, University of Southern California, Marina del Rey, CA, USA.ORCID http://orcid.org/0000-0003-4401-8950
Christopher R K ChingImaging Genetics Center, Mark & Mary Stevens Neuroimaging and Informatics Institute, Keck School of Medicine, University of Southern California, Marina del Rey, CA, USA.
Sophia I ThomopoulosImaging Genetics Center, Mark & Mary Stevens Neuroimaging and Informatics Institute, Keck School of Medicine, University of Southern California, Marina del Rey, CA, USA.ORCID http://orcid.org/0000-0002-0046-4070
Eric VernerTri-Institutional Center for Translational Research in Neuroimaging and Data Science (TReNDS), Georgia State University, Georgia Institute of Technology, Emory University, Atlanta, GA, 30303, USA.ORCID http://orcid.org/0000-0002-1461-4818
Gregory P StraussDepartments of Psychology and Neuroscience, University of Georgia, Athens, GA, USA.ORCID http://orcid.org/0000-0002-7218-5169
Anthony O AhmedWeill Cornell Medicine, Department of Psychiatry, White Plains, NY, 10605, USA.
Matthew D TurnerPsychology Department, Georgia State University, Atlanta, GA, USA.ORCID http://orcid.org/0000-0002-4417-1042
Sunitha BasodiTri-Institutional Center for Translational Research in Neuroimaging and Data Science (TReNDS), Georgia State University, Georgia Institute of Technology, Emory University, Atlanta, GA, 30303, USA.
Judith M FordVeterans Affairs San Francisco Healthcare System, San Francisco, CA, 94121, USA.
Daniel H MathalonVeterans Affairs San Francisco Healthcare System, San Francisco, CA, 94121, USA.
Adrian PredaDepartment of Psychiatry and Human Behavior, University of California Irvine, University of California Irvine Medical Center, 101 The City Drive S, Orange, CA, 92868, USA.ORCID http://orcid.org/0000-0003-3373-2438
Aysenil BelgerDepartment of Psychiatry and Frank Porter Graham Child Development Institute, University of North Carolina at Chapel Hill, 105 Smith Level Road, Chapel Hill, NC, 27599-8180, USA.ORCID http://orcid.org/0000-0003-2687-1966
Bryon A MuellerDepartment of Psychiatry and Behavioral Sciences, University of Minnesota, Minneapolis, MN, 55414, USA.ORCID http://orcid.org/0000-0003-2429-0391
Kelvin O LimDepartment of Psychiatry and Behavioral Sciences, University of Minnesota, Minneapolis, MN, 55414, USA.ORCID http://orcid.org/0000-0002-2390-7268
Theo G M van ErpClinical Translational Neuroscience Laboratory, Department of Psychiatry and Human Behavior, University of California Irvine, 5251 California Ave, Irvine, CA, 92617, USA.ORCID http://orcid.org/0000-0002-2465-2797
University of Southern California · USGeorgia Institute of Technology · USGeorgia State University · USUniversity of California, San Francisco · USUniversity of Minnesota · USCornell University · USUniversity of California, Irvine · USUniversity of California, Irvine Medical Center · USUniversity of Georgia · USUniversity of North Carolina at Chapel Hill · US

Funding

FUNCTION BIRNU24RR021992 · NCRR · UNIVERSITY OF CALIFORNIA-IRVINE · PI POTKIN, STEVEN G · 2006 to 2010
$25.0M
BIO-INFORMATICS RESEARCH NETWORK COORDINATING CENTER (BIRN-CC)U24RR025736 · NCRR · UNIVERSITY OF SOUTHERN CALIFORNIA · PI KESSELMAN, CARL · 2009 to 2011
$15.0M
TR&D3: Intrinsic Surface MappingP41EB015922 · NIBIB · UNIVERSITY OF SOUTHERN CALIFORNIA · PI VAN HORN, JOHN DARRELL · 2012 to 2022
$14.1M
COINSTAC: Decentralized, Scalable Analysis of Loosely Coupled DataR01DA040487 · NIDA · THE MIND RESEARCH NETWORK · PI CALHOUN, VINCE D, PLIS, SERGEY · 2015 to 2024
$7.1M
ENIGMA-COINSTAC-APOE2 Functional and structural connectome protective mechanisms for Alzheimer’s disease and mood disorders: Request for supplemental funds for NIH R01:1R01MH121246R01MH121246 · NIMH · OHIO STATE UNIVERSITY · PI CALHOUN, VINCE D, TURNER, JESS · 2019 to 2023
$5.0M
A decentralized macro and micro gene-by-environment interaction analysis of substance use behavior and its brain biomarkers R01DA049238 · NIDA · GEORGIA STATE UNIVERSITY · PI CALHOUN, VINCE D, LIU, JINGYU · 2019 to 2023
$2.9M
ENIGMA-SD: Understanding Sex Differences in Global Mental Health through ENIGMAR01MH116147 · NIMH · UNIVERSITY OF SOUTHERN CALIFORNIA · PI THOMPSON, PAUL M · 2018 to 2021
$2.5M
A global alliance to unlock brain mechanisms influencing suicidal behaviors through the ENIGMA ConsortiumR01MH117601 · NIMH · UNIVERSITY OF SOUTHERN CALIFORNIA · PI JAHANSHAD, NEDA, SCHMAAL, LIANNE · 2018 to 2021
$1.5M
NCRR NIH HHS U24 RR021992NCRR NIH HHS U24 RR025736NIBIB NIH HHS P41 EB015922NIDA NIH HHS R01 DA040487NIDA NIH HHS R01 DA049238NIMH NIH HHS R01 MH116147NIMH NIH HHS R01 MH117601NIMH NIH HHS R01 MH121246
6 · The paper itself

Abstract

The FAIR principles, as applied to clinical and neuroimaging data, reflect the goal of making research products Findable, Accessible, Interoperable, and Reusable. The use of the Collaborative Informatics and Neuroimaging Suite Toolkit for Anonymized Computation (COINSTAC) platform in the Enhancing Neuroimaging Genetics through Meta-Analysis (ENIGMA) consortium combines the technological approach of decentralized analyses with the sociological approach of sharing data. In addition, ENIGMA + COINSTAC provides a platform to facilitate the use of machine-actionable data objects. We first present how ENIGMA and COINSTAC support the FAIR principles, and then showcase their integration with a decentralized meta-analysis of sex differences in negative symptom severity in schizophrenia, and finally present ongoing activities and plans to advance FAIR principles in ENIGMA + COINSTAC. ENIGMA and COINSTAC currently represent efforts toward improved Access, Interoperability, and Reusability. We highlight additional improvements needed in these areas, as well as future connections to other resources for expanded Findability.

Indexed as

NeuroimagingFemaleHumansMaleCOINSTACData privacyDecentralizedENIGMAMeta-analysis

Identifiers

PMID34846691
PMCPMC9149142
OpenAlexW3215992528

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.