ArticlePloS one2021
Relationships of sex hormones with muscle mass and muscle strength in male adolescents at different stages of puberty.
Article in PloS one, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
18 citing papers in PubMed, 1 synthesis or guideline pooled it, 31 citations in OpenAlex.
- Brazilian Guideline for Exercise Testing in Children and Adolescents - 2024.Arquivos brasileiros de cardiologia · 2024Guideline
- A mobile app-based intervention improves anthropometry, body composition and fitness, regardless of previous active-inactive status: a randomized controlled trial.Frontiers in public health · 2024Trial
- Handgrip Strength in Korean Youth and Young Adults: Reference Values and Their Associations with Metabolic Syndrome.Journal of obesity & metabolic syndrome · 2026Article
- The anatomical knowledge of Namibian school children.Anatomical sciences education · 2026Article
- The effect of high intensity interval training on body composition, metabolic, inflammatory and oxidative stress markers in adolescents with obesity.Diabetology & metabolic syndrome · 2026Article
- School-based predictive contributors to six-minute walk test performance across pubertal stages: an explainable machine learning study in Tunisian adolescents.Frontiers in sports and active living · 2026Article
- Sex-Specific Morphological and Neuromuscular Profiles of U-15 Colombian Basketball Players.Journal of functional morphology and kinesiology · 2025Article
- Gender Differences in Lower Limb Strength and Endurance Among Saudi Adolescents: A Cross-Sectional Study on the Limited Role of Body Mass Index.Children (Basel, Switzerland) · 2025Article
- Reliability of the biceps curl test and proposed percentiles in schoolchildren living at moderate altitude in Peru.Scientific reports · 2025Article
- Sex differences in quantitative ultrasonographic measurements of the rectus femoris in children.Journal of anatomy · 2025Article
- Challenging the principle of "No presumption of advantage" with a focus on testosterone and gender eligibility in sports.Frontiers in sports and active living · 2025Review
- An In Vivo Model of Estrogen Supplementation Concerning the Expression of CaJournal of cardiovascular development and disease · 2024Article
- Gender-specific Indian Paediatric and Adult Reference Data for Muscle Function Parameters Assessed Using Jumping Mechanography.Journal of musculoskeletal & neuronal interactions · 2024Article
- Aromatase Inhibitors May Increase the Risk of Cardiometabolic Complications in Adolescent Boys.Pediatric cardiology · 2024Review
- Relationship between muscle power, muscle volume and limb length in healthy male and female adolescents.Frontiers in sports and active living · 2024Article
- Anterior Cruciate Ligament Rehabilitation for the 10- to 18-Year-Old Adolescent Athlete: Practice Guidelines Based on International Delphi Consensus.Orthopaedic journal of sports medicine · 2023Article
- Sex differences in body composition affect total airway resistance during puberty.BMC pediatrics · 2022Article
- Teacher-Rated Executive Functions, Gender and Relative Age: Independent and Interactive Effects on Observed Fundamental Motor Skills in Kindergarteners.Frontiers in psychology · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
This study analysed the associations of sex steroids with fat-free mass (FFM) and handgrip strength in 641 Chinese boys. Serum total testosterone (TT) and oestradiol were measured by chemiluminescence immunoassay. Free testosterone (FT) and oestradiol were calculated. FFM and handgrip strength were measured by bioelectrical impedance analysis and a hand dynamometer, respectively. Generalised additive models and multiple linear regression were used to explore the relationships. A subgroup analysis was conducted in early-mid pubertal and late-post pubertal groups. Age, height, weight, physical activity, intake of dietary protein and/or stage of puberty were adjusted. TT and FT were positively related to FFM and handgrip strength, with a curvilinear relationship being detected for handgrip strength (p<0.050). This curvilinear relationship was only observed in the late-post pubertal group, suggesting a potential threshold effect (FT>11.99ng/dL, β = 1.275, p = 0.039). In the early-mid pubertal group, TT and/or FT were linearly or near-linearly related to FFM or handgrip strength (β = 0.003-0.271, p<0.050). The association between FT and FFM was stronger than that in the late-post pubertal group. This study found that serum T had different associations with muscle parameters in Chinese early-mid pubertal and late-post pubertal boys. In the late-post pubertal boys, serum T was curvilinearly related to muscle strength with a threshold effect and its link with muscle mass was weaker.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.