ArticleBiomedical optics express2021
Three-dimensional dynamics optical coherence tomography for tumor spheroid evaluation.
Article in Biomedical optics express, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 49 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
49 citing papers in PubMed, 1 synthesis or guideline pooled it, 82 citations in OpenAlex.
- Unlocking the Potential of Spheroids in Personalized Medicine: A Systematic Review of Seeding Methodologies.International journal of molecular sciences · 2025Pooled it
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- First-order field autocorrelation function analysis-based dynamic OCT for tissue viability assessment.Biomedical optics express · 2026Article
- High-speed full-field swept-source dynamic optical coherence tomography enabled by neural-network-based image generation.Biomedical optics express · 2026Article
- AI-Driven Breast Cancer Diagnosis: A Systematic Review of Imaging Modalities, Deep Learning, and Explainability.Cancers · 2026Review
- Dynamic full-field swept-source optical coherence tomography for high-resolution, long-depth, and intratissue-activity imaging.Biomedical optics express · 2026Article
- Dynamic optical coherence microscope integrated with cell-cultivation chamber enabled longitudinal and early-stage assessment of tumor spheroid-drug interaction.Scientific reports · 2026Article
- Article
- Longitudinal investigation of prostate tumor spheroid proliferation with dynamic line-field optical coherence tomography.Biomedical optics express · 2026Article
- A 3-dimensional Resnet model for assessment of drug efficacy in 3D cancer models using optical coherence tomography.PloS one · 2026Article
- Label-free viability assessment ofBiomedical optics express · 2026Article
- Dynamic optical coherence tomography algorithm for label-free assessment of swiftness and occupancy of intratissue moving scatterers.Biomedical optics express · 2026Article
- Review of dynamic optical coherence tomography for intracellular motility: signals, metrics, and their applications [Invited].Biomedical optics express · 2025Review
- Developmental Imaging of Radish Sprouts Using Dynamic Optical Coherence Tomography.Journal of biophotonics · 2025Article
- Guide to dynamic OCT data analysis.Biomedical optics express · 2025Article
- Real-Time Viability Assessment of Ex Vivo Mouse Kidneys for Transplant Applications Using Dynamic Optical Coherence Tomography.bioRxiv : the preprint server for biology · 2025Article
- Three-dimensional dynamic optical coherence tomography for breast tumor margin assessment.Biomedical optics express · 2025Article
- Experimental and numerical investigation of wavelength and resolution dependency of dynamic optical coherence tomography signals.Biomedical optics express · 2025Article
- Dynamic-OCT simulation framework based on mathematical models of intratissue dynamics, image formation, and measurement noise.Biomedical optics express · 2025Article
- Biochemical state in tissue can be detected through ultrasound signal.npj biomedical innovations · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 3 institutions in 4 countries.
Funding
Abstract
We present a completely label-free three-dimensional (3D) optical coherence tomography (OCT)-based tissue dynamics imaging method for visualization and quantification of the metabolic and necrotic activities of tumor spheroid. Our method is based on a custom 3D scanning protocol that is designed to capture volumetric tissue dynamics tomography images only in a few tens of seconds. The method was applied to the evaluation of a tumor spheroid. The time-course viability alteration and anti-cancer drug response of the spheroid were visualized qualitatively and analyzed quantitatively. The similarity between the OCT-based dynamics images and fluorescence microscope images was also demonstrated.
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.