Evidence map›Paper›PMID 34858879›Full record

ArticleFrontiers in cellular and infection microbiology2021

Effective Genome Editing in

Caroline R Espada, José Carlos Quilles, Andreia Albuquerque-Wendt, Mario C Cruz, Tom Beneke, Lucas B Lorenzon, Eva Gluenz, Angela K Cruz, Silvia R B Uliana

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in cellular and infection microbiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
2.2field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 20 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
  4. Review
  5. Article
  6. Article
  7. Review
  8. Article
  9. Life in plastic, it's fantastic! HowFrontiers in cellular and infection microbiology · 2023
    Review
  10. Review
  11. Reporter gene systems: A powerful tool forCurrent research in microbial sciences · 2022
    Article
  12. Gene editing of putative cAMP and CaThe Journal of eukaryotic microbiology
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 3 countries.

Caroline R EspadaDepartamento de Parasitologia, Instituto de Ciências Biomédicas, Universidade de São Paulo, São Paulo, Brazil.
José Carlos QuillesDepartamento de Biologia Celular e Molecular, Faculdade de Medicina de Ribeirão Preto, Universidade de São Paulo (FMRP-USP), Ribeirão Preto, Brazil.
Andreia Albuquerque-WendtSir William Dunn School of Pathology, University of Oxford, Oxford, United Kingdom.
Mario C CruzCentro de Facilidades para Apoio à Pesquisa, Universidade de São Paulo (CEFAP-USP), São Paulo, Brazil.
Tom BenekeSir William Dunn School of Pathology, University of Oxford, Oxford, United Kingdom.
Lucas B LorenzonDepartamento de Biologia Celular e Molecular, Faculdade de Medicina de Ribeirão Preto, Universidade de São Paulo (FMRP-USP), Ribeirão Preto, Brazil.
Eva GluenzSir William Dunn School of Pathology, University of Oxford, Oxford, United Kingdom.
Angela K CruzDepartamento de Biologia Celular e Molecular, Faculdade de Medicina de Ribeirão Preto, Universidade de São Paulo (FMRP-USP), Ribeirão Preto, Brazil.
Silvia R B UlianaDepartamento de Parasitologia, Instituto de Ciências Biomédicas, Universidade de São Paulo, São Paulo, Brazil.
Universidade de São Paulo · BRUniversidade de Ribeirão Preto · BRInstituto de Investigação Científica Tropical · PTUniversity of Oxford · GBWellcome Centre for Molecular Parasitology · GB

Funding

Medical Research Council 15/16_MSD_836338Wellcome TrustWellcome Trust 104111/Z/14/Z
6 · The paper itself

Abstract

Until 2015, loss-of-function studies to elucidate protein function in

Indexed as

Leishmania braziliensisLeishmania majorCRISPR-Cas SystemsDNA-Directed RNA PolymerasesGene EditingViral Proteinsbacteriophage T7 RNA polymeraseDNA-Directed RNA PolymerasesViral ProteinsCRISPR/Cas9endogenous taggingknockoutLeishmania braziliensisPF16reverse genetics

Identifiers

PMID34858879
PMCPMC8631273
OpenAlexW3213773234

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.