Evidence map›Paper›PMID 34858883›Full record

ArticleFrontiers in cellular and infection microbiology2021

Mining Anti-Inflammation Molecules From

Yuying Chen, Mingming Zhang, Xin Ding, Yougui Yang, Yujia Chen, Qiang Zhang, Yinwen Fan, Yang Dai, Junhong Wang

Abstract read
In one paragraph

Article in Frontiers in cellular and infection microbiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Protective effects ofFrontiers in immunology · 2025
    Article
  5. Article
  6. Review
  7. Article
  8. Inhibition Effects ofPathogens (Basel, Switzerland) · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Yuying ChenCenter for Global Health, School of Public Health, Nanjing Medical University, Nanjing, China.
Mingming ZhangDepartment of Cardiology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China.
Xin DingKey Laboratory of National Health Commission on Parasitic Disease Control and Prevention, Key Laboratory of Jiangsu Province on Parasite and Vector Control Technology, Jiangsu Institute of Parasitic Diseases, Wuxi, China.
Yougui YangCenter for Global Health, School of Public Health, Nanjing Medical University, Nanjing, China.
Yujia ChenDepartment of Cardiology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China.
Qiang ZhangKey Laboratory of National Health Commission on Parasitic Disease Control and Prevention, Key Laboratory of Jiangsu Province on Parasite and Vector Control Technology, Jiangsu Institute of Parasitic Diseases, Wuxi, China.
Yinwen FanDepartment of Cardiology, The Friendship Hospital of Ili Kazakh Autonomous Prefecture Ili & Jiangsu Joint Institute of Health, Ili, China.
Yang DaiCenter for Global Health, School of Public Health, Nanjing Medical University, Nanjing, China.
Junhong WangDepartment of Cardiology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hookworm is one type of soil-transmitted helminth, which could exert an anti-inflammatory effect in human or animal host, which provides a beneficial possibility for the discovery of inflammatory-related disease interventions. The identification of hookworm-derived anti-inflammatory molecules is urgently needed for future translational research. The emergence of metabolomics has become a powerful approach to comprehensively characterize metabolic alterations in recent times. Herein, excretory and secretory products (ESPs) were collected from cultured adult worm, while small intestinal contents were obtained from

Indexed as

MetabolomicsNippostrongylusAnimalsAnti-Inflammatory AgentsMass SpectrometryMiceProteomicsAnti-Inflammatory Agentsanti-inflammatory activityhookwormhost–pathogen interactionsmetabolomics approachNippostrongylus brasiliensis

Identifiers

PMID34858883
PMCPMC8632049

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.