ArticleScience advances2021
MON-2, a Golgi protein, mediates autophagy-dependent longevity in
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Article in Science advances, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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18citing papers in PubMed
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Who cites it
18 citing papers in PubMed.
- Caffeine extends lifespan by enhancing lysosomal lipolysis in Caenorhabditis elegans.Molecules and cells · 2026Article
- MAK-2 Kinase Is Required for Extended Longevity and Enhanced Stress Resistance Resulting From Mild Impairment of Mitochondrial Function in isp-1 Mutants.Aging cell · 2026Article
- Aging-associated decline of phosphatidylcholine synthesis is a malleable trigger of natural mitochondrial aging.Nature communications · 2026Article
- FAM177A1 disrupts SIRT3-SOD2 signaling to drive mitochondrial dysfunction-mediated VSMC phenotypic switching in vascular remodeling.International journal of biological sciences · 2026Article
- Multilayered regulation of longevity in Caenorhabditis elegans.Molecules and cells · 2026Review
- Integrating GWAS meta-analysis with human brain cell mapping implicates the amygdala and the midbrain in the pathogenesis of tinnitus.medRxiv : the preprint server for health sciences · 2025Article
- Pelota-mediated ribosome-associated quality control counteracts aging and age-associated pathologies across species.Proceedings of the National Academy of Sciences of the United States of America · 2025Article
- Brief guide to Caenorhabditis elegans survival assays.Molecules and cells · 2025Review
- Combinatorial transcriptomic and genetic dissection of insulin/IGF-1 signaling-regulated longevity in Caenorhabditis elegans.Aging cell · 2024Article
- TFAM is an autophagy receptor that limits inflammation by binding to cytoplasmic mitochondrial DNA.Nature cell biology · 2024Article
- Longevity interventions modulate mechanotransduction and extracellular matrix homeostasis in C. elegans.Nature communications · 2024Article
- Distinct pathways for export of silencing RNA iniScience · 2023Article
- Article
- Smooth Muscle Cell Phenotypic Switch Induced by Traditional Cigarette Smoke Condensate: A Holistic Overview.International journal of molecular sciences · 2023Article
- Endosomal trafficking protein TBC-2 is required for the longevity of long-lived mitochondrial mutants.Frontiers in aging · 2023Article
- The lipid flippase Drs2 regulates anterograde transport of Atg9 during autophagy.Autophagy reports · 2022Article
- Dietary regulation in health and disease.Signal transduction and targeted therapy · 2022Review
- MON-2, a Golgi protein, promotes longevity by upregulating autophagy through mediating inter-organelle communications.Autophagy · 2022Article
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Authors and funding
29 authors.
Yoonji JungDepartment of Biological Sciences, Korea Advanced Institute of Science and Technology, 291 Daehak-ro, Yuseong-gu, Daejeon 34141, South Korea.ORCID 0000-0003-1557-2645
Murat ArtanDepartment of Life Sciences, Pohang University of Science and Technology, 77 Cheongam-ro, Nam-gu, Pohang, Gyeongbuk 37673, South Korea.ORCID 0000-0001-8945-6992
Nari KimDepartment of Life Sciences, Pohang University of Science and Technology, 77 Cheongam-ro, Nam-gu, Pohang, Gyeongbuk 37673, South Korea.ORCID 0000-0003-4837-9278
Jeonghun YeomCenter for Theragnosis, Korea Institute of Science and Technology, Seoul 02792, South Korea.ORCID 0000-0001-9577-1243
Ara B HwangDepartment of Life Sciences, Pohang University of Science and Technology, 77 Cheongam-ro, Nam-gu, Pohang, Gyeongbuk 37673, South Korea.ORCID 0000-0002-8045-2474
Dae-Eun JeongDepartment of Life Sciences, Pohang University of Science and Technology, 77 Cheongam-ro, Nam-gu, Pohang, Gyeongbuk 37673, South Korea.
Özlem AltintasDepartment of Life Sciences, Pohang University of Science and Technology, 77 Cheongam-ro, Nam-gu, Pohang, Gyeongbuk 37673, South Korea.
Keunhee SeoDepartment of Life Sciences, Pohang University of Science and Technology, 77 Cheongam-ro, Nam-gu, Pohang, Gyeongbuk 37673, South Korea.ORCID 0000-0003-1490-2083
Mihwa SeoDepartment of Life Sciences, Pohang University of Science and Technology, 77 Cheongam-ro, Nam-gu, Pohang, Gyeongbuk 37673, South Korea.
Dongyeop LeeDepartment of Life Sciences, Pohang University of Science and Technology, 77 Cheongam-ro, Nam-gu, Pohang, Gyeongbuk 37673, South Korea.ORCID 0000-0001-8973-5430
Wooseon HwangDepartment of Life Sciences, Pohang University of Science and Technology, 77 Cheongam-ro, Nam-gu, Pohang, Gyeongbuk 37673, South Korea.ORCID 0000-0002-4591-029X
Yujin LeeDepartment of Biological Sciences, Korea Advanced Institute of Science and Technology, 291 Daehak-ro, Yuseong-gu, Daejeon 34141, South Korea.
Jooyeon SohnDepartment of Biological Sciences, Korea Advanced Institute of Science and Technology, 291 Daehak-ro, Yuseong-gu, Daejeon 34141, South Korea.ORCID 0000-0001-9071-9390
Eun Ji E KimDepartment of Biological Sciences, Korea Advanced Institute of Science and Technology, 291 Daehak-ro, Yuseong-gu, Daejeon 34141, South Korea.
Sungeun JuDepartment of Life Sciences, Pohang University of Science and Technology, 77 Cheongam-ro, Nam-gu, Pohang, Gyeongbuk 37673, South Korea.ORCID 0000-0002-8597-3850
Seong Kyu HanDepartment of Life Sciences, Pohang University of Science and Technology, 77 Cheongam-ro, Nam-gu, Pohang, Gyeongbuk 37673, South Korea.
Hyun-Jun NamDepartment of Life Sciences, Pohang University of Science and Technology, 77 Cheongam-ro, Nam-gu, Pohang, Gyeongbuk 37673, South Korea.ORCID 0000-0002-1745-3896
Linnea AdamsDevelopment, Aging, and Regeneration Program, Sanford Burnham Prebys Medical Discovery Institute, 10901 North Torrey Pines Road, La Jolla, CA 92037, USA.
Youngjae RyuResearch Division and Brain Research Core Facilities of Korea Brain Research Institute, Daegu 41068, South Korea.
Dong Jin MoonDepartment of Life Sciences, Pohang University of Science and Technology, 77 Cheongam-ro, Nam-gu, Pohang, Gyeongbuk 37673, South Korea.ORCID 0000-0001-9448-3311
Chanhee KangSchool of Biological Sciences, College of Natural Sciences, Seoul National University, 1 Gwanak-ro, Gwanak-gu, Seoul 08826, South Korea.ORCID 0000-0003-4350-5706
Joo-Yeon YooDepartment of Life Sciences, Pohang University of Science and Technology, 77 Cheongam-ro, Nam-gu, Pohang, Gyeongbuk 37673, South Korea.ORCID 0000-0001-5942-3989
Sang Ki ParkDepartment of Life Sciences, Pohang University of Science and Technology, 77 Cheongam-ro, Nam-gu, Pohang, Gyeongbuk 37673, South Korea.ORCID 0000-0003-1023-7864
Chang Man HaResearch Division and Brain Research Core Facilities of Korea Brain Research Institute, Daegu 41068, South Korea.
Malene HansenDevelopment, Aging, and Regeneration Program, Sanford Burnham Prebys Medical Discovery Institute, 10901 North Torrey Pines Road, La Jolla, CA 92037, USA.
Sanguk KimDepartment of Life Sciences, Pohang University of Science and Technology, 77 Cheongam-ro, Nam-gu, Pohang, Gyeongbuk 37673, South Korea.ORCID 0000-0002-3449-3814
Cheolju LeeCenter for Theragnosis, Korea Institute of Science and Technology, Seoul 02792, South Korea.ORCID 0000-0001-8482-4696
Seung-Yeol ParkDepartment of Life Sciences, Pohang University of Science and Technology, 77 Cheongam-ro, Nam-gu, Pohang, Gyeongbuk 37673, South Korea.ORCID 0000-0001-5061-4535
Seung-Jae V LeeDepartment of Biological Sciences, Korea Advanced Institute of Science and Technology, 291 Daehak-ro, Yuseong-gu, Daejeon 34141, South Korea.ORCID 0000-0002-6103-156X
Funding
Attenuation of cancellous osteopenia by in vivo loadingR01AG028664 · NIA · CORNELL UNIVERSITY · PI VAN DER MEULEN, MARJOLEIN C · 2006 to 2009
$1.0MNIA NIH HHS R01 AG028664
Abstract
The Golgi apparatus plays a central role in trafficking cargoes such as proteins and lipids. Defects in the Golgi apparatus lead to various diseases, but its role in organismal longevity is largely unknown. Using a quantitative proteomic approach, we found that a Golgi protein, MON-2, was up-regulated in long-lived
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LicenceCC BY-NC
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.