Evidence map›Paper›PMID 34865504›Full record

ReviewHypertension (Dallas, Tex. : 1979)2022

BBSome: a New Player in Hypertension and Other Cardiovascular Risks.

Yuying Zhao, Kamal Rahmouni

Open access · bronzeAbstract readReview
In one paragraph

Review in Hypertension (Dallas, Tex. : 1979), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
2.4field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 19 citations in OpenAlex.

  1. Review
  2. Article
  3. Ciliary Defects in Inherited Retinal Diseases.Advanced genetics (Hoboken, N.J.) · 2026
    Review
  4. Review
  5. Article
  6. Adipocyte-specific disruption of the BBSome causes metabolic and autonomic dysfunction.American journal of physiology. Regulatory, integrative and comparative physiology · 2024
    Article
  7. Article
  8. Metabolic consequences of skeletal muscle- and liver-specific BBSome deficiency.American journal of physiology. Endocrinology and metabolism · 2023
    Article
  9. Article
  10. Review
  11. Article
  12. T cell-specific deficiency in BBSome component BBS1 interferes with selective immune responses.American journal of physiology. Regulatory, integrative and comparative physiology · 2023
    Article
  13. Article
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Yuying ZhaoDepartment of Neuroscience and Pharmacology (Y.Z., K.R.), University of Iowa Carver College of Medicine, Iowa City.
Kamal RahmouniDepartment of Neuroscience and Pharmacology (Y.Z., K.R.), University of Iowa Carver College of Medicine, Iowa City.ORCID 0000-0001-5136-6748
University of Iowa · US

Funding

Role of the brain Renin-Angiotensin Sys. in Cardiovas and Metabolic RegulationP01HL084207 · NHLBI · UNIVERSITY OF IOWA · PI GROBE, JUSTIN L · 2007 to 2022
$30.2M
Neuronal Mechanisms of Obesity-Induced HypertensionI01BX004249 · VA · IOWA CITY VA MEDICAL CENTER · PI KAMAL RAHMOUNI · 2019 to 2026
–
BLRD VA I01 BX004249NHLBI NIH HHS P01 HL084207
6 · The paper itself

Abstract

The BBSome is an octameric protein complex involved in Bardet-Biedl syndrome (BBS), a human pleiotropic, autosomal recessive condition. Patients with BBS display various clinical features including obesity, hypertension, and renal abnormalities. Association studies have also linked the

Indexed as

AnimalsBardet-Biedl SyndromeBlood PressureCell LineHumansHypertensionRisk FactorsBardet-Biedl syndromeblood pressureheart diseasekidney diseaseobesity

Identifiers

PMID34865504
PMCPMC8755612
OpenAlexW4200227712

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.