Evidence map›Paper›PMID 34868539›Full record

ReviewJournal of tissue engineering

Freeform 3D printing of vascularized tissues: Challenges and strategies.

Hyun Lee, Tae-Sik Jang, Ginam Han, Hae-Won Kim, Hyun-Do Jung

Abstract readReview
In one paragraph

Review in Journal of tissue engineering. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed.

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  9. Biofabrication of engineered blood vessels for biomedical applications.Science and technology of advanced materials · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Hyun LeeDepartment of Biomedical and Chemical Engineering (BMCE), The Catholic University of Korea, Bucheon, Republic of Korea.
Tae-Sik JangDepartment of Materials Science and Engineering, Chosun University, Gwangju, Republic of Korea.
Ginam HanDepartment of Biomedical and Chemical Engineering (BMCE), The Catholic University of Korea, Bucheon, Republic of Korea.
Hae-Won KimInstitute of Tissue Regeneration Engineering (ITREN), Dankook University, Cheonan, Chungcheongnam-do, Republic of Korea.ORCID https://orcid.org/0000-0001-6400-6100
Hyun-Do JungDepartment of Biomedical and Chemical Engineering (BMCE), The Catholic University of Korea, Bucheon, Republic of Korea.ORCID https://orcid.org/0000-0001-8632-7431

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In recent years, freeform three-dimensional (3D) printing has led to significant advances in the fabrication of artificial tissues with vascularized structures. This technique utilizes a supporting matrix that holds the extruded printing ink and ensures shape maintenance of the printed 3D constructs within the prescribed spatial precision. Since the printing nozzle can be translated omnidirectionally within the supporting matrix, freeform 3D printing is potentially applicable for the fabrication of complex 3D objects, incorporating curved, and irregular shaped vascular networks. To optimize freeform 3D printing quality and performance, the rheological properties of the printing ink and supporting matrix, and the material matching between them are of paramount importance. In this review, we shall compare conventional 3D printing and freeform 3D printing technologies for the fabrication of vascular constructs, and critically discuss their working principles and their advantages and disadvantages. We also provide the detailed material information of emerging printing inks and supporting matrices in recent freeform 3D printing studies. The accompanying challenges are further discussed, aiming to guide freeform 3D printing by the effective design and selection of the most appropriate materials/processes for the development of full-scale functional vascularized artificial tissues.

Indexed as

Additive manufacturingartificial tissuesfreeform 3D printingtissue engineeringvascularized structures

Identifiers

PMID34868539
PMCPMC8638074

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.