Evidence mapPaperPMID 34868943Full record

SynthesisFrontiers in oncology2021

Physical Therapies for Psychosomatic Symptoms and Quality of Life Induced by Aromatase Inhibitors in Breast Cancer Patients: A Systematic Review and Meta-Analysis.

Xue-Ying Zhu, Zhong Li, Cong Chen, Ru-Li Feng, Bai-Ru Cheng, Ruo-Yi Liu, Rui-Ting Wang, Li Xu, Yue Wang, Xin Tao and 1 more

Open access · goldAbstract readSystematic Review
In one paragraph

Synthesis in Frontiers in oncology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 2 pooled it
1.5field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 2 syntheses or guidelines pooled it, 22 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Trial
  4. Review
  5. Article
  6. Review
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

Xue-Ying ZhuDepartment of Oncology, Dongzhimen Hospital, Beijing University of Chinese Medicine, Beijing, China.
Zhong LiDepartment of Oncology, Dongzhimen Hospital, Beijing University of Chinese Medicine, Beijing, China.
Cong ChenDepartment of Cardiology, Dongzhimen Hospital, Beijing University of Chinese Medicine, Beijing, China.
Ru-Li FengDepartment of Cardiology, Dongzhimen Hospital, Beijing University of Chinese Medicine, Beijing, China.
Bai-Ru ChengDepartment of Cardiology, Dongzhimen Hospital, Beijing University of Chinese Medicine, Beijing, China.
Ruo-Yi LiuDepartment of Encephalopathy, Dongzhimen Hospital, Beijing University of Chinese Medicine, Beijing, China.
Rui-Ting WangDepartment of Cardiology, Dongzhimen Hospital, Beijing University of Chinese Medicine, Beijing, China.
Li XuDepartment of Gynecology, Dongzhimen Hospital, Beijing University of Chinese Medicine, Beijing, China.
Yue WangGraduate School of Beijing University of Chinese Medicine, Beijing, China.
Xin TaoSchool of Medical Humanities, Capital Medical University, Beijing, China.
Peng ZhaoDepartment of Cardiology, Dongzhimen Hospital, Beijing University of Chinese Medicine, Beijing, China.
Dongzhimen Hospital Affiliated to Beijing University of Chinese Medicine · CNBeijing University of Chinese Medicine · CNCapital Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo evaluate the effects of Physical Therapies (PTs) on improvement in psychosomatic symptoms and quality of life (QOL) in breast cancer patients. DATA SOURCES: Seven databases (MEDLINE, EMBASE, Cochrane CENTRAL, China National Knowledge Infrastructure, Wangfang, VIP, and China Biology Medicine disc databases) were systematically searched from the database inception through May 18, 2021. STUDY SELECTION: Randomized controlled trials (RCTs) which compared acupuncture or exercise with a sham control or usual care for the treatment of aromatase inhibitors (AIs)-related psychosomatic symptoms and QOL. DATA EXTRACTION AND SYNTHESIS: Data were screened and extracted independently using predesigned forms. The quality of RCTs was assessed with the Cochrane Handbook for Systematic Reviews of Interventions. The effect size was calculated MAIN OUTCOMES AND MEASURES: The score of pain was measured with BPI scale and Western Ontario and the McMaster Universities Index (WOMAC) scale. Emotional state was measured with Pittsburgh Sleep Quality Index (PSQI), Hospital Anxiety and Depression Scale (HADS-A), and Functional Assessment of Chronic Illness Therapy-Fatigue (FACIT-Fatigue). The QOL score was measured by self-reported measurements, including the Functional Assessment of Cancer Therapy-General (FACT-G) scale and 36-Item Short Form Survey (SF-36) scale.

resultsEleven RCTs (with 830 patients) were included in the systematic review, and data from 10 RCTs (with 798 patients) were used in the meta-analysis. Results showed acupuncture significantly reduced worst pain scores ( CONCLUSIONS AND RELEVANCE: This systematic review and meta-analysis suggested that based on moderate-level evidence, acupuncture was associated with significant reductions in pain intensity, and exercise might improve QOL in breast cancer patients treated with AIs. However, in psychosomatic symptoms such as anxiety, sleep disturbance, and fatigue, acupuncture and exercise training did not result in significant improvements.

Indexed as

acupuncturearomatase inhibitorsbreast cancerexercisepainphysical therapiesquality of life

Identifiers

PMID34868943
PMCPMC8632958
OpenAlexW3212079713

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.