ArticleScientific reports2021
Green synthesis of bimetallic ZnO-CuO nanoparticles and their cytotoxicity properties.
Article in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 43 papers.
What it found
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
43 citing papers in PubMed.
- Polysaccharide-stabilized biogenic CuO/SeORSC advances · 2026Article
- Foliar application of green-synthesized Cu-Zn nanocomposites: improve physiological responses, isozymes activity, and photosynthetic traits in lead-stressed pea (Pisum sativum L.) plants.Scientific reports · 2026Article
- Article
- Nephrotoxicity Evaluation of Green and Chemically Synthesized Copper Oxide Nanoparticles in Rats: A Biochemical and Genotoxic Approach.Current pharmaceutical design · 2026Article
- Biosynthesized bimetallic nanoparticles containing CeOScientific reports · 2025Article
- Electrochemical biosensing in oncology: a review advancements and prospects for cancer diagnosis.Cancer biology & therapy · 2025Review
- Harnessing copper oxide nanoparticles for advanced photocatalytic, antimicrobial, and larvicidal applications.Scientific reports · 2025Article
- Cannabis sativa-mediated biosynthesis of copper-zinc-selenium nanocomposites: phytochemical profiling, antioxidant properties, and molecular docking insights.Journal of cannabis research · 2025Article
- Synthesis, characterization and bioactivity of chalcone-based polybenzoxazine/copper oxide nanocomposites.RSC advances · 2025Article
- Unveiling the potency of ZnO and CuO nanocomposites in combating hepatocellular carcinoma by inducing cell death and suppressing migration.Scientific reports · 2025Article
- Potential Therapeutic Effect of ZnO/CuO Nanocomposite as an Acaricidal, Immunostimulant, and Antioxidant in Rabbits.Veterinary sciences · 2025Article
- An Overview of the Bioactivity of Spontaneous Medicinal Plants Suitable for the Improvement of Lung Cancer Therapies.Pharmaceutics · 2025Review
- Article
- Article
- Anticancer, antimicrobial and antioxidant activity of CuO-ZnO bimetallic nanoparticles: green synthesised from Eryngium foetidum leaf extract.Scientific reports · 2024Article
- Biogenic nanoparticles: pioneering a new era in breast cancer therapeutics-a comprehensive review.Discover nano · 2024Review
- Article
- Biosynthesis of ZnO, BiChemistryOpen · 2024Article
- Facile synthesis of FeScientific reports · 2024Article
- The potential of copper oxide nanoparticles in nanomedicine: A comprehensive review.Biotechnology notes (Amsterdam, Netherlands) · 2024Review
Corrections and comments
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Authors and funding
13 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
In this study, a simple and green strategy was reported to prepare bimetallic nanoparticles (NPs) by the combination of zinc oxide (ZnO) and copper oxide (CuO) using Sambucus nigra L. extract. The physicochemical properties of these NPs such as crystal structure, size, and morphology were studied by X-ray diffraction (XRD), field emission gun scanning electron microscopy (FEG-SEM), and transmission electron microscopy (TEM). The results suggested that these NPs contained polygonal ZnO NPs with hexagonal phase and spherical CuO NPs with monoclinic phase. The anticancer activity of the prepared bimetallic NPs was evaluated against lung and human melanoma cell lines based on MTT assay. As a result, the bimetallic ZnO/CuO NPs exhibited high toxicity on melanoma cancer cells while their toxicity on lung cancer cells was low.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.