Evidence map›Paper›PMID 34873482›Full record

ArticleAmerican journal of cancer research2021

Noncoding RNAs: emerging players in skin cancers pathogenesis.

Lin Li, Suliman Khan, Song Li, Shengchun Wang, Fang Wang

Open access · greenAbstract read
In one paragraph

Article in American journal of cancer research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.1field-weighted citation impact, top 54% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Lin LiDepartment of Dermatology, The Affiliated Children's Hospital of Zhengzhou University Zhengzhou 450053, Henan, China.
Suliman KhanDepartment of Cerebrovascular Diseases, The Second Affiliated Hospital of Zhengzhou University Zhengzhou 450014, Henan, China.
Song LiDepartment of Dermatology, The Affiliated Children's Hospital of Zhengzhou University Zhengzhou 450053, Henan, China.
Shengchun WangDepartment of Dermatology, The Affiliated Children's Hospital of Zhengzhou University Zhengzhou 450053, Henan, China.
Fang WangDepartment of Dermatology, The Affiliated Children's Hospital of Zhengzhou University Zhengzhou 450053, Henan, China.
Zhengzhou Children's Hospital · CNUniversity of Haripur · PK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Skin malignancies form in tissues of the skin and are the most frequent cancers in the world, with an increasing incidence and a steady fatality rate. They are classified as melanoma or nonmelanoma cancers, which include basal cell carcinoma and squamous cell carcinoma. Noncoding RNA transcripts have received increased attention after the thorough analysis of the human genome revealed that most of the genomic components are not encoded to protein. MicroRNAs, long noncoding RNAs, and circular RNAs are some of the well-studied types of these noncoding regions. The alteration in any of these members' expression is associated intrinsically with human cancers, including skin malignancies, due to their critical functions in cell processes for normal development. As a result, investigating the noncoding component of the transcriptome opens up the possibility of discovering new therapeutic and diagnostic targets. This review discusses current studies on the involvement of microRNAs, long noncoding RNAs, and circular RNAs in the pathogenesis of human skin cancers.

Indexed as

circRNAlncRNAmicroRNASkin cancer

Identifiers

PMID34873482
PMCPMC8640824
OpenAlexW4206865251

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.