ArticlePloS one2021
A comparative study of hematological parameters between hypertensive and normotensive individuals in Harar, eastern Ethiopia.
Article in PloS one, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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17 citing papers in PubMed, 21 citations in OpenAlex.
- A Prospective Observational Study: Are There Any Relationships Between Erythrocytosis, Renal Tubular-Glomerular Functions, and Systemic Hypertension in Adolescent Male Idiopathic Erythrocytosis Patients?Children (Basel, Switzerland) · 2026Article
- Hypertension and its associated risk factors in tuberculosis patients: A hospital based cross-sectional study.Asia Pacific journal of clinical nutrition · 2026Article
- Magnitude and Predictors of Leukopenia and Thrombocytopenia in Adults With HIV/AIDS Attending Mizan Tepi University Teaching Hospital, Southwest Ethiopia.BioMed research international · 2026Article
- The relationship between hypertension, anemia, and BMI in women of reproductive age: evidence from a nationwide health study.BMC cardiovascular disorders · 2025Article
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- Hematological parameters of hypertensive patients in northeast Ethiopia: A comparative cross-sectional study.Heliyon · 2024Article
- White blood cell and platelet distribution widths are associated with hypertension: data mining approaches.Hypertension research : official journal of the Japanese Society of Hypertension · 2024Article
- Platelet Indices and Hypertension: Results from Shahedieh Cohort Study, Yazd, Iran.International journal of hypertension · 2024Article
- Association between complete blood-count-based inflammatory scores and hypertension in persons living with and without HIV in Zambia.PloS one · 2024Article
- Association Between Hemoglobin Level, Anemia, and Hypertension Among Adults in Northern Sudan: A Community-Based Cross-Sectional Study.Vascular health and risk management · 2024Article
- The association between red cell distribution width and newly diagnosed hypertension among adults in Northern Sudan: a case-control study.The Libyan journal of medicine · 2023Article
- Red Cell Distribution Width and Prediabetes in Adults in Northern Sudan: A Case-Control Study.Hematology reports · 2023Article
- SARS-CoV-2 Impact on Red Blood Cell Morphology.Biomedicines · 2023Article
- The associations between hematological parameters and the incidence of prehypertension and hypertension in children and adolescents: a prospective cohort study.Hypertension research : official journal of the Japanese Society of Hypertension · 2023Article
- Evaluation of Mean Platelet Volume in Children with Hypertension.International journal of hypertension · 2023Article
- A Critical Analysis of the Automated Hematology Assessment in Pregnant Women at Low and at High Altitude: Association between Red Blood Cells, Platelet Parameters, and Iron Status.Life (Basel, Switzerland) · 2022Article
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Authors and funding
3 authors at 2 institutions in 1 country.
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No grant is acknowledged in the PubMed record.
Abstract
backgroundHypertension is the major public health concern; leading to cardiovascular disease. It is associated with alteration in hematological parameters which may lead to end-organ damage. Thus, this study aimed to compare hematological parameters between hypertensive and normotensive adult groups in Harar, eastern Ethiopia.
methodsA comparative cross-sectional study was conducted from January to March, 2020 at Jugel and Hiwotfana Specialized University hospital, Harar, eastern Ethiopia. Convenient sampling technique was used to recruit 102 hypertensive patients from the two hospitals and 102 apparently healthy blood donors. Participant's socio-demographic and clinical information were collected using pre-tested structured questionnaire. Blood sample were collected and analyzed by Beckman Coulter DxH 500 analyzer for complete blood count. The data were entered and analyzed using SPSS version 23. Independent t-test and Mann Whitney u-test was used for comparison between groups. Spearman's correlation was used for correlation test. P values less than 0.05 was considered as statistically significant.
result102 hypertensive and 102 healthy controls were enrolled in this study. The median ± IQR value of white blood cell (WBC) count, hemoglobin (Hgb), hematocrit (HCT), red cell distribution width (RDW) and mean platelet volume (MPV) were significantly higher in hypertensive group compared to apparently healthy control group. Additionally, RBC (red blood cell) count, HCT and RDW showed statistically significant positive correlations with systolic and diastolic blood pressure. WBC count and RDW were significantly and positively correlated with body mass index (BMI). Platelet (PLT) count had a significant but negative correlation (r = -0.219, P = 0.027) with duration of hypertension illness while MPV showed positive and significant correlation (r = 0.255, P = 0.010).
conclusionThe median values of WBC, Hgb, HCT, RDW and MPV were significantly higher in hypertensive patient compared to apparently healthy individuals. Hence, it is important to assess hematological parameters for hypertensive individuals which may help to prevent complications associated with hematological aberrations. However, further studies are required to understand hypertensive associated changes in hematological parameters.
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