Evidence map›Paper›PMID 34878634›Full record

ArticleAIDS and behavior2022

Identification of Youthful Neurocognitive Trajectories in Adults Aging with HIV: A Latent Growth Mixture Model.

Rowan Saloner, Judith D Lobo, Emily W Paolillo, Laura M Campbell, Scott L Letendre, Mariana Cherner, Igor Grant, Robert K Heaton, Ronald J Ellis, Scott C Roesch and 2 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in AIDS and behavior, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Rowan SalonerSan Diego Joint Doctoral Program in Clinical Psychology, San Diego State University/University of California, San Diego, CA, USA. rsaloner@health.ucsd.edu.ORCID http://orcid.org/0000-0002-1351-6183
Judith D LoboDepartment of Psychiatry, HIV Neurobehavioral Research Program, University of California, San Diego, 220 Dickinson Street, Suite B, Mail Code 8231, San Diego, CA, 92103-8231, USA.
Emily W PaolilloSan Diego Joint Doctoral Program in Clinical Psychology, San Diego State University/University of California, San Diego, CA, USA.
Laura M CampbellSan Diego Joint Doctoral Program in Clinical Psychology, San Diego State University/University of California, San Diego, CA, USA.
Scott L LetendreDepartment of Psychiatry, HIV Neurobehavioral Research Program, University of California, San Diego, 220 Dickinson Street, Suite B, Mail Code 8231, San Diego, CA, 92103-8231, USA.
Mariana ChernerDepartment of Psychiatry, HIV Neurobehavioral Research Program, University of California, San Diego, 220 Dickinson Street, Suite B, Mail Code 8231, San Diego, CA, 92103-8231, USA.
Igor GrantDepartment of Psychiatry, HIV Neurobehavioral Research Program, University of California, San Diego, 220 Dickinson Street, Suite B, Mail Code 8231, San Diego, CA, 92103-8231, USA.
Robert K HeatonDepartment of Psychiatry, HIV Neurobehavioral Research Program, University of California, San Diego, 220 Dickinson Street, Suite B, Mail Code 8231, San Diego, CA, 92103-8231, USA.
Ronald J EllisDepartment of Psychiatry, HIV Neurobehavioral Research Program, University of California, San Diego, 220 Dickinson Street, Suite B, Mail Code 8231, San Diego, CA, 92103-8231, USA.
Scott C RoeschDepartment of Psychology, San Diego State University, San Diego, CA, USA.
David J MooreDepartment of Psychiatry, HIV Neurobehavioral Research Program, University of California, San Diego, 220 Dickinson Street, Suite B, Mail Code 8231, San Diego, CA, 92103-8231, USA.
CHARTER Study Group

Funding

STRUCTURAL NEUROIMAGING COREP30MH062512 · NIMH · UNIVERSITY OF CALIFORNIA, SAN DIEGO · 2001 to 2025
$15.2M
Training in Research on Addictions in Interdisciplinary NeuroAIDS (TRAIN)T32DA031098 · UNIVERSITY OF CALIFORNIA, SAN DIEGO · 2025 to 2025
$438k
Mentoring Clinical Researchers at the Intersection of NeuroHIV and Substance AbuseK24DA040550 · UNIVERSITY OF CALIFORNIA, SAN DIEGO · 2025 to 2025
$192k
CNS HIV ANTI-RETROVIRAL THERAPY EFFECTS RESEARCH /CHARTER/-278022005N01MH022005 · UNIVERSITY OF CA -SAN DIEGO · 2003 to 2005
–
NIAAA NIH HHS F31 AA027198NIAAA NIH HHS F31AA027198NIA NIH HHS F31 AG064989NIA NIH HHS F31AG064989NIA NIH HHS F31 AG067869NIA NIH HHS F31AG067869NIDA NIH HHS K24 DA040550NIDA NIH HHS T32 DA031098NIDA NIH HHS T32DA031098NIH HHS HHSN271201000036CNIMH NIH HHS HHSN271201000036CNIMH NIH HHS N01 MH022005NIMH NIH HHS N01MH2205NIMH NIH HHS P30 MH062512NIMH NIH HHS R01 MH107345NIMH NIH HHS R01MH107345
6 · The paper itself

Abstract

Despite the neurocognitive risks of aging with HIV, initial cross-sectional data suggest a subpopulation of older people with HIV (PWH) possess youthful neurocognition (NC) characteristic of SuperAgers (SA). Here we characterize longitudinal NC trajectories of older PWH and their convergent validity with baseline SA status, per established SuperAging criteria in PWH, and baseline biopsychosocial factors. Growth mixture modeling (GMM) identified longitudinal NC classes in 184 older (age ≥ 50-years) PWH with 1-5 years of follow-up. Classes were defined using 'peak-age' global T-scores, which compare performance to a normative sample of 25-year-olds. 3-classes were identified: Class 1

Indexed as

HIV InfectionsAdultAgedAgingCross-Sectional StudiesHumansMiddle AgedCognitive reserveComorbidity burdenGrowth mixture modelHIV-associated neurocognitive disorderSuperAging

Identifiers

PMID34878634
PMCPMC9046348

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.