ArticleEuropean journal of endocrinology2022
Long-term body composition improvement in post-menopausal women following bariatric surgery: a cross-sectional and case-control study.
Article in European journal of endocrinology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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Who cites it
6 citing papers in PubMed, 9 citations in OpenAlex.
- Twelve-Month BMI and Metabolic Changes After Roux-en-Y Gastric Bypass in Women with Severe Obesity.Journal of clinical medicine · 2026Article
- Impact of Menopausal Status on Bone Metabolism and Body Composition After Metabolic-Bariatric Surgery: a Two-Year Prospective Study in Middle-Aged Women.Obesity surgery · 2026Article
- Impact of Menopausal Status and Female Reproductive Aging on the Outcomes of Bariatric Surgery: A Narrative Review.Cureus · 2026Review
- Sarcopenia, Muscle Mass and Protein Intake in Adults Older Than 65 Years After Earlier Bariatric Surgery.Journal of cachexia, sarcopenia and muscle · 2025Observational
- Body Composition Changes and Predictor of Weight Loss in Short Term after Sleeve Gastrectomy.Obesity surgery · 2025Article
- Changes in Lean Tissue Mass, Fat Mass, Biological Parameters and Resting Energy Expenditure over 24 Months Following Sleeve Gastrectomy.Nutrients · 2023Article
Corrections and comments
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Authors and funding
8 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveBariatric surgery (BS) induces loss of body fat mass (FM) with an inexorable loss of lean mass (LM). Menopause leads to deleterious changes in body composition (BC) related to estrogen deficiency including LM loss and increase in total and visceral adipose tissue (VAT). This study aims to describe the long-term weight evolution of post-menopausal women after Roux-en-Y gastric bypass (RYGB) and to compare the BC between BS patients vs post-menopausal non-operated women.
designCross-sectional study of 60 post-menopausal women who underwent RYGB ≥2 years prior to the study with nested case-control design.
methodsPost-menopausal BS women were matched for age and BMI with controls. Both groups underwent DXA scan, lipids and glucose metabolism markers assessment.
resultsMedian follow-up was 7.5 (2-18) years. Percentage of total weight loss (TWL%) was 28.5 ± 10%. After RYGB, LM percentage of body weight (LM%) was positively associated with TWL% and negatively associated with nadir weight. Forty-one post-BS women were age- and BMI-matched with controls. Post-BS patients showed higher LM% (57.7% (±8%) vs 52.5% (±5%), P = 0.001), reduced FM% (39.4% (±8.4%) vs 45.9% (±5.4%), P < 0.01) and lower VAT (750.6 g (±496) vs 1295.3 g (±688), P < 0.01) with no difference in absolute LM compared to controls. While post-BS women showed a better lipid profile compared to controls, no difference was found in glucose markers.
conclusionsPost-menopausal women after RYGB have a lower FM and VAT, preserved LM and a better lipid profile compared to controls. Weight loss after RYGB seems to have a persistent positive impact on metabolic health.
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