Evidence map›Paper›PMID 34879861›Full record

Observational studyBMC neurology2021

Critical issue on the extinction and inattention subtest of NIHSS scale: an analysis on post-acute stroke patients attending inpatient rehabilitation.

Benedetta Basagni, Bahia Hakiki, Silvia Campagnini, Emilia Salvadori, Antonello Grippo, Anita Paperini, Chiara Castagnoli, Ines Hochleitner, Angela Maria Politi, Paola Gemignani and 10 more

Registry-linked trialAbstract readMulticenter StudyObservational Study
In one paragraph

Observational study in BMC neurology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03968627 (Development of a National, Evidence Based Protocol for Stroke Rehabilitation in a Multicenter Italian no Profit Institution), which is not on this map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03968627 completednot on this map

Development of a National, Evidence Based Protocol for Stroke Rehabilitation in a Multicenter Italian no Profit Institution: Implementation and Results of a Pilot Study

TypeobservationalSponsorFondazione Don Carlo Gnocchi ETSRan2017 to 2018Enrolled443ConditionsStroke, RehabilitationArmsRehabilitative intervention
3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Review
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors.

Benedetta BasagniIRCCS Fondazione Don Carlo Gnocchi, Via di Scandicci 269 -, 50143, Florence, Italy.
Bahia HakikiIRCCS Fondazione Don Carlo Gnocchi, Via di Scandicci 269 -, 50143, Florence, Italy.
Silvia CampagniniIRCCS Fondazione Don Carlo Gnocchi, Via di Scandicci 269 -, 50143, Florence, Italy. scampagnini@dongnocchi.it.
Emilia SalvadoriIRCCS Fondazione Don Carlo Gnocchi, Via di Scandicci 269 -, 50143, Florence, Italy.
Antonello GrippoIRCCS Fondazione Don Carlo Gnocchi, Via di Scandicci 269 -, 50143, Florence, Italy.
Anita PaperiniIRCCS Fondazione Don Carlo Gnocchi, Via di Scandicci 269 -, 50143, Florence, Italy.
Chiara CastagnoliIRCCS Fondazione Don Carlo Gnocchi, Via di Scandicci 269 -, 50143, Florence, Italy.
Ines HochleitnerIRCCS Fondazione Don Carlo Gnocchi, Via di Scandicci 269 -, 50143, Florence, Italy.
Angela Maria PolitiIRCCS Fondazione Don Carlo Gnocchi, Via di Scandicci 269 -, 50143, Florence, Italy.
Paola GemignaniIRCCS Fondazione Don Carlo Gnocchi, Via di Scandicci 269 -, 50143, Florence, Italy.
Irene Eleonora MoscaIRCCS Fondazione Don Carlo Gnocchi, Via di Scandicci 269 -, 50143, Florence, Italy.
Azzurra FranceschiniIRCCS Fondazione Don Carlo Gnocchi, Via di Scandicci 269 -, 50143, Florence, Italy.
Enrico Bacci BonottiIRCCS Fondazione Don Carlo Gnocchi, Via di Scandicci 269 -, 50143, Florence, Italy.
Alessandro SoderoIRCCS Fondazione Don Carlo Gnocchi, Via di Scandicci 269 -, 50143, Florence, Italy.
Andrea ManniniIRCCS Fondazione Don Carlo Gnocchi, Via di Scandicci 269 -, 50143, Florence, Italy.
Leonardo PellicciariIRCCS Fondazione Don Carlo Gnocchi, Via di Scandicci 269 -, 50143, Florence, Italy.
Anna PoggesiIRCCS Fondazione Don Carlo Gnocchi, Via di Scandicci 269 -, 50143, Florence, Italy.
Claudio MacchiIRCCS Fondazione Don Carlo Gnocchi, Via di Scandicci 269 -, 50143, Florence, Italy.
Maria Chiara CarrozzaThe Biorobotics Institute, Scuola Superiore Sant'Anna, Pontedera, Italy.
Francesca CecchiIRCCS Fondazione Don Carlo Gnocchi, Via di Scandicci 269 -, 50143, Florence, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesThis study aims to evaluate the diagnostic performance of NIHSS extinction and inattention item, compared to the results of the Oxford Cognitive Screen (OCS) heart subtest. Additionally, the possible role of the NIHSS visual field subtest on the NIHSS extinction and inattention subtest performance is explored and discussed.

methodsWe analysed scores on NIHSS extinction and inattention subtest, NIHSS visual field subtest, and OCS heart subtest on a sample of 118 post-stroke patients.

resultsCompared to OCS heart subtest, the results on NIHSS extinction and inattention subtest showed an accuracy of 72.9% and a moderate agreement level (Cohen's kappa = 0.404). Furthermore, a decrease in NIHSS accuracy detecting neglect (61.1%) was observed in patients with pathological scores in NIHSS visual field item.

conclusionsExtreme caution is recommended for the diagnostic performance of extinction and inattention item of NIHSS. Signs of neglect may not be detected by NIHSS, and may be confused with visual field impairment.

trial registrationThis study refers to an observational study protocol submitted to ClinicalTrials.gov with identifier: NCT03968627 . The name of the registry is "Development of a National Protocol for Stroke Rehabilitation in a Multicenter Italian Institution" and the date of the registration is the 30th May 2019.

Indexed as

StrokeStroke RehabilitationCognitionHumansInpatientsRegistriesSeverity of Illness IndexHeminattentionHemineglectNIHSSRehabilitationStrokeVisual field

Identifiers

PMID34879861
PMCPMC8653531

What Socratic holds

Textmetadata
LicenceCC BY
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.