Evidence map›Paper›PMID 34883502›Full record

ReviewComplex psychiatry2020

FMRP and CYFIP1 at the Synapse and Their Role in Psychiatric Vulnerability.

Nicholas E Clifton, Kerrie L Thomas, Lawrence S Wilkinson, Jeremy Hall, Simon Trent

Open access · hybridAbstract readReview
In one paragraph

Review in Complex psychiatry, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
2.5field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 27 citations in OpenAlex.

  1. Article
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  5. Review
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  9. Review
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  11. Article
  12. Prader-Willi Syndrome and Chromosome 15q11.2 BP1-BP2 Region: A Review.International journal of molecular sciences · 2023
    Review
  13. Article
  14. Article
  15. Review
  16. Article
  17. Biomarkers in schizophrenia - past, present and future.Romanian journal of morphology and embryology = Revue roumaine de morphologie et embryologie
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Nicholas E CliftonNeuroscience & Mental Health Research Institute, Cardiff University, Cardiff, United Kingdom.
Kerrie L ThomasNeuroscience & Mental Health Research Institute, Cardiff University, Cardiff, United Kingdom.
Lawrence S WilkinsonNeuroscience & Mental Health Research Institute, Cardiff University, Cardiff, United Kingdom.
Jeremy HallNeuroscience & Mental Health Research Institute, Cardiff University, Cardiff, United Kingdom.
Simon TrentNeuroscience & Mental Health Research Institute, Cardiff University, Cardiff, United Kingdom.
Cardiff University · GB

Funding

Medical Research Council MR/L010305/1
6 · The paper itself

Abstract

There is increasing awareness of the role genetic risk variants have in mediating vulnerability to psychiatric disorders such as schizophrenia and autism. Many of these risk variants encode synaptic proteins, influencing biological pathways of the postsynaptic density and, ultimately, synaptic plasticity. Fragile-X mental retardation 1 (

Indexed as

Cytoplasmic FMRP-interacting protein 1Fragile-X mental retardation proteinFragile-X mental retardation protein targetsPsychiatric disordersSynapse

Identifiers

PMID34883502
PMCPMC7673588
OpenAlexW3010485710

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.