ArticleBMC pediatrics2021
Red flags of poor prognosis in pediatric cases of COVID-19: the first 6610 hospitalized children in Iran.
Article in BMC pediatrics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 3 of them syntheses that pooled it.
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Who cites it
17 citing papers in PubMed, 3 syntheses or guidelines pooled it, 52 citations in OpenAlex.
- Risk Factors for Pediatric Critical COVID-19: A Systematic Review and Meta-Analysis.Journal of the Pediatric Infectious Diseases Society · 2024Pooled it
- Guidance for prevention and management of COVID-19 in children and adolescents: A consensus statement from the Pediatric Infectious Diseases Society Pediatric COVID-19 Therapies Taskforce.Journal of the Pediatric Infectious Diseases Society · 2024Pooled it
- Epidemiology and clinical features of SARS-CoV-2 infection in children and adolescents in the pre-Omicron era: A global systematic review and meta-analysis.Journal of global health · 2024Pooled it
- Vaccination in Children with Chronic Kidney Disease: Current Status and Perspectives.Vaccines · 2025Review
- Longitudinal analysis of Covid-19 infection trends and in-hospital mortality across six pandemic waves in Tunisia.Archives of public health = Archives belges de sante publique · 2025Article
- The severity of pediatric COVID-19 during hospitalization is not associated with mortality within six months of discharge.BMC pediatrics · 2025Article
- Epidemic profile of COVID-19 child deaths in Sri Lanka: a retrospective nationwide analysis.BMC pediatrics · 2025Article
- Fulminant coronavirus disease 2019 meningitis in Iranian infants: a case series.Journal of medical case reports · 2024Article
- Risk Factors for Pediatric Critical COVID-19: A Systematic Review and Meta-Analysis.medRxiv : the preprint server for health sciences · 2024Article
- Analysis of factors associated with admission to the intensive care unit of children and adolescents with COVID-19: application of a multilevel model.Critical care science · 2024Article
- Clinical characteristics of COVID-19 in children: a large multicenter study from Iran.Frontiers in pediatrics · 2024Article
- 'Inequalities in prevalence of hypertension, prehypertension, anti-hypertensive coverage, awareness, and effective treatment in 429 districts of Iran; a population-based STEPS 2016 small area spatial estimation model'.Journal of diabetes and metabolic disorders · 2023Article
- Clinical and laboratory characteristics of children with severe and nonsevere COVID-19 in Kermanshah, west of Iran: A retrospective study.Health science reports · 2023Article
- Characteristics and clinical outcomes of COVID-19 in children: a hospital-based surveillance study in Latin America's hardest-hit city.IJID regions · 2023Article
- Survival and Mortality in Hospitalized Children with COVID-19: A Referral Center Experience in Yazd, Iran.The Canadian journal of infectious diseases & medical microbiology = Journal canadien des maladies infectieuses et de la microbiologie medicale · 2023Article
- In-hospital mortality of COVID-19 in Iranian children and youth: A multi-centre retrospective cohort study.Journal of global health · 2022Article
- Survival analysis and mortality predictors of COVID-19 in a pediatric cohort in Mexico.Frontiers in public health · 2022Article
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Authors and funding
15 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionCOVID-19 clinical course, effective therapeutic regimen, and poor prognosis risk factors in pediatric cases are still under investigation and no approved vaccinehas been introduced for them.
methodsThis cross-sectional study evaluated different aspect of COVID-19 infection in hospitalized COVID-19 positive children (≺18 years oldwith laboratory confirmed COVID-19 infection, using the national COVID-19 registry for all admitted COVID-19 positive cases from February 19 until November 13,2020, in Iran.
resultsWe evaluated 6610 hospitalized children. Fifty-four percent (3268) were male and one third of them were infants younger than 1 year. Mortality rate in total hospitalized children was 5.3% and in children with underlying co-morbidities (14.4%) was significantly higher (OR: 3.6 [2.7-4.7]). Chronic kidney disease (OR: 3.42 [1.75-6.67]), Cardiovascular diseases (OR: 3.2 [2.09-5.11]), chronic pulmonary diseases (OR: 3.21 [1.59-6.47]), and diabetes mellitus (OR: 2.5 [1.38-4.55]), resulted in higher mortality rates in hospitalized COVID-19 children. Fever (41%), cough (36%), and dyspnea (27%) were the most frequent symptoms in hospitalized children and dyspnea was associated with near three times higher mortality rate among children with COVID-19 infection (OR: 2.65 [2.13-3.29]).
conclusionIran has relatively high COVID-19 mortality in hospitalized children. Pediatricians should consider children presenting with dyspnea, infants≺ 1 year and children with underlying co-morbidities, as high-risk groups for hospitalization, ICU admission, and death.
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