Evidence map›Paper›PMID 34893821›Full record

ArticleClinical infectious diseases : an official publication of the Infectious Diseases Society of America2022

Incidence of Invasive Fungal Infections in Patients Initiating Ibrutinib and Other Small Molecule Kinase Inhibitors-United States, July 2016-June 2019.

Jeremy A W Gold, Seda S Tolu, Tom Chiller, Kaitlin Benedict, Brendan R Jackson

Open access · hybridAbstract read
In one paragraph

Article in Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 2 pooled it
2.0field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 2 syntheses or guidelines pooled it, 23 citations in OpenAlex.

  1. Pooled it
  2. Guideline
  3. Article
  4. A breakthrough invasiveMedical mycology case reports · 2026
    Article
  5. Dematiaceous Molds.Infectious disease clinics of North America · 2025
    Review
  6. Case reports in infectious diseases · 2025
    Article
  7. Review
  8. Article
  9. Article
  10. Review
  11. Review
  12. Article
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  14. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Jeremy A W GoldMycotic Diseases Branch, Centers for Disease Control and Prevention, Atlanta, Georgia, USA.ORCID 0000-0002-5054-7616
Seda S ToluDivision of Hematology/Oncology, Columbia University Irving Medical Center, New York, New York, USA.
Tom ChillerMycotic Diseases Branch, Centers for Disease Control and Prevention, Atlanta, Georgia, USA.
Kaitlin BenedictMycotic Diseases Branch, Centers for Disease Control and Prevention, Atlanta, Georgia, USA.
Brendan R JacksonMycotic Diseases Branch, Centers for Disease Control and Prevention, Atlanta, Georgia, USA.
Centers for Disease Control and Prevention · USColumbia University Irving Medical Center · US

Funding

Intramural CDC HHS CC999999
6 · The paper itself

Abstract

We analyzed administrative data to determine the 1-year incidence of invasive fungal infections (IFIs) in patients beginning small molecule kinase inhibitor (SMKI) therapy. The incidence of IFIs by small molecule kinase inhibitor ranged from 0.0% to 10.6%, with patients taking midostaurin having the highest incidence. An IFI developed in 38 of 1286 patients taking ibrutinib (3.0%).

Indexed as

AdenineInvasive Fungal InfectionsPiperidinesHumansIncidenceUnited StatesAdenineibrutinibPiperidinescanceribrutinibinvasive fungal infectionsopportunistic infectionssmall molecule kinase inhibitors

Identifiers

PMID34893821
PMCPMC9184298
OpenAlexW4200104636

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.