ReviewEuropean journal of medical research2021
Update on pathogenesis and diagnosis flow of normoalbuminuric diabetes with renal insufficiency.
Review in European journal of medical research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
8 citing papers in PubMed.
- Serum Uric Acid to Creatinine Ratio as a Predictor of Normoalbuminuric DKD in T2DM with Normal Renal Function.International journal of general medicine · 2026Article
- TGF-β: elusive target in diabetic kidney disease.Renal failure · 2025Review
- Article
- Therapeutic effect of Corbrin (Bailing) capsule on patients with renal insufficiency: A meta-analysis.Heliyon · 2024Article
- [Non-Classical Clinical Types and Pathological Changes of Diabetic Kidney Disease: A Review].Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition · 2023Review
- New strategies to improve clinical outcomes for diabetic kidney disease.BMC medicine · 2022Review
- Re-understanding and focusing on normoalbuminuric diabetic kidney disease.Frontiers in endocrinology · 2022Review
- Urinary Biomarker Profiles Define Divergent Pathways in Albuminuric and Non-Albuminuric Diabetic Kidney Disease.Kidney diseases (Basel, Switzerland)Article
Corrections and comments
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Authors and funding
3 authors.
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Abstract
In recent decades, the prevalence of diabetic kidney disease has remained stable and appears to be a wide heterogeneity. Normoalbuminuric diabetes with renal insufficiency, which is characterized by a decline in the glomerular filtration rate in the absence of albuminuria, has been identified as an albuminuria-independent phenotype of diabetic kidney disease. Epidemiological data demonstrate that normoalbuminuric phenotype is prevalent. Compared to albuminuric phenotype, normoalbuminuric phenotype has distinct clinical characteristics and a wide heterogeneity of pathological features. Currently, the pathogenesis of normoalbuminuric phenotype remains unclear. Additionally, the flow of diagnosing normoalbuminuric phenotype is not perfect. In this article, we review the latest studies addressing the epidemiology, clinical characteristics, and pathology of normoalbuminuric phenotype. Based on the studies of clinical features and renal histopathologic changes, we attempt to propose an underlying pathogenesis model and a flow chart for diagnosing normoalbuminuric phenotype.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.