Evidence map›Paper›PMID 34895463›Full record

ArticleeLife2021

John Rp Knight, Nikola Vlahov, David M Gay, Rachel A Ridgway, William James Faller, Christopher Proud, Giovanna R Mallucci, Tobias von der Haar, Christopher Mark Smales, Anne E Willis and 1 more

Open access · goldAbstract read
In one paragraph

Article in eLife, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
1.7field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 26 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 2 countries.

John Rp KnightCRUK Beatson Institute, Garscube Estate, Glasgow, United Kingdom.ORCID 0000-0002-8771-5484
Nikola VlahovCRUK Beatson Institute, Garscube Estate, Glasgow, United Kingdom.
David M GayCRUK Beatson Institute, Garscube Estate, Glasgow, United Kingdom.
Rachel A RidgwayCRUK Beatson Institute, Garscube Estate, Glasgow, United Kingdom.
William James FallerCRUK Beatson Institute, Garscube Estate, Glasgow, United Kingdom.
Christopher ProudDepartment of Biological Sciences, University of Adelaide, Adelaide, Australia.
Giovanna R MallucciUK Dementia Research Institute at the University of Cambridge and Department of Clinical Neurosciences, University of Cambridge, Cambridge, United Kingdom.
Tobias von der HaarSchool of Biosciences, Division of Natural Sciences, University of Kent, Kent, United Kingdom.ORCID 0000-0002-6031-9254
Christopher Mark SmalesSchool of Biosciences, Division of Natural Sciences, University of Kent, Kent, United Kingdom.
Anne E WillisMRC Toxicology Unit, University of Cambridge, Cambridge, United Kingdom.ORCID 0000-0002-1470-8531
Owen J SansomCRUK Beatson Institute, Garscube Estate, Glasgow, United Kingdom.ORCID 0000-0001-9540-3010
Cancer Research UK Scotland Institute · GBUniversity of Cambridge · GBUniversity of Kent · GBSouth Australian Health and Medical Research Institute · AU

Funding

Cancer Research UK 21139Cancer Research UK A17196Cancer Research UK A21139Cancer Research UK A24388Medical Research Council MC_UP_A600_1023Medical Research Council MC_UU_00025/7Wellcome Trust 201487
6 · The paper itself

Abstract

Increased protein synthesis supports the rapid cell proliferation associated with cancer. The

Indexed as

MutationSignal TransductionAnimalsColorectal NeoplasmsDisease Models, AnimalElongation Factor 2 KinaseFemaleMaleMiceMice, TransgenicPhosphorylationRibosomal ProteinsEef2k protein, mouseElongation Factor 2 Kinaseribosomal protein L24Ribosomal Proteinscancer biologycell biologyeEF2Kintestinal cancerin vivo modelsmouseprotein sythesisRPL24translation

Identifiers

PMID34895463
PMCPMC8668188
OpenAlexW4225650011

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.