Evidence map›Paper›PMID 34895515›Full record

ArticleMolecular therapy : the journal of the American Society of Gene Therapy2022

Cardiac reprogramming via chromatin remodeling by CRISPR activation.

James W S Jahng, Joseph C Wu

Abstract readComment
PubMed Full text at PMC Publisher
In one paragraph

Article in Molecular therapy : the journal of the American Society of Gene Therapy, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors.

James W S JahngStanford Cardiovascular Institute, Stanford University, School of Medicine, Stanford, USA.
Joseph C WuStanford Cardiovascular Institute, Stanford University, School of Medicine, Stanford, USA; Division of Cardiovascular Medicine, Department of Medicine, Stanford University, School of Medicine, Stanford, USA; Department of Radiology, Stanford University, School of Medicine, Stanford, USA. Electronic address: joewu@stanford.edu.

Funding

Elucidating Mechanism of Cardiac Fibrosis with Cell Village of Pooled Human iPSCsR01HL130020 · NHLBI · STANFORD UNIVERSITY · PI Ronglih Liao, MARK MERCOLA · 2016 to 2026
$7.3M
Genome Editing of Human iPSCs to Study Inherited Hypertrophic CardiomyopathyR01HL126527 · NHLBI · STANFORD UNIVERSITY · PI QI, LEI STANLEY, WU, JOSEPH C. · 2015 to 2022
$5.4M
Precision Medicine for Heart Failure: The Role of Genomics in the Efficacy and Racial Disparity of Cornerstone PharmacotherapyK08HL146990 · NHLBI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI LUZUM, JASMINE A · 2019 to 2023
$772k
NHLBI NIH HHS K08 HL146990NHLBI NIH HHS R01 HL126527NHLBI NIH HHS R01 HL130020
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Chromatin Assembly and DisassemblyInduced Pluripotent Stem CellsCellular ReprogrammingClustered Regularly Interspaced Short Palindromic Repeats

Identifiers

PMID34895515
PMCPMC8753518

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.