Evidence map›Paper›PMID 34896064›Full record

ReviewJornal de pediatria

Climate changes, air pollution and allergic diseases in childhood and adolescence.

Marilyn Urrutia-Pereira, Guillermo Guidos-Fogelbach, Dirceu Solé

Open access · goldAbstract readReview
In one paragraph

Review in Jornal de pediatria. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
4.1field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 55 citations in OpenAlex.

  1. Cord blood DNA methylation as a potential mediator in the association between prenatal ambient air pollution and early infant allergic symptoms in a Shanghai birth cohort.Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology · 2026
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  12. Gene-environment interactions in childhood asthma revisited; expanding the interaction concept.Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 3 institutions in 2 countries.

Marilyn Urrutia-PereiraUniversidade Federal do Pampa, Departamento de Medicina, Pampa, RS, Brazil.
Guillermo Guidos-FogelbachInstituto Politécnico Nacional, Escuela Nacional de Medicina y Homeopatía, Postgraduate Department, Mexico City, Mexico.
Dirceu SoléUniversidade Federal de São Paulo, Escola Paulista de Medicina, Departamento de Pediatria, Divisão de Alergia, Imunologia Clínica e Reumatologia, São Paulo, SP, Brazil. Electronic address: sole.dirceu@gmail.com.
Associação Brasileira de Alergia e Imunologia · BRInstituto Politécnico Nacional · MXUniversidade Federal do Pampa · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo analyze the impacts of climate change on the development of immature respiratory and immune systems in children. SOURCE OF DATA: The authors of the present study performed a non-systematic review of English, Spanish, and Portuguese articles published in the last five years in databases such as PubMed, EMBASE, and SciELO. The terms used were air pollution OR climate changes OR smoke, AND children OR health. SYNTHESIS OF DATA: The increase in the prevalence of some diseases, such as allergic ones, is attributed to the interactions between genetic potential and the environment. However, disordered growth combined with inadequate waste management has caused problems for the planet, such as heatwaves, droughts, forest fires, increased storms and floods, interference in food crops and their nutritional values, changes in the infectious disease pattern, and air pollution resulting from the continuous use of fossil fuels. Children, beings still in the development stage with immature respiratory and immune systems, are the primary victims of the climate crisis.

conclusionsThe authors documented that prenatal and postnatal exposure to ambient air pollutants will accelerate or worsen the morbidity and mortality of many health conditions, including allergic diseases. Ambient air pollutants change the microbiota, interfere with the immune response, and take direct action on the skin and respiratory epithelium, which facilitates the penetration of allergens. Understanding how the children and adolescent health and well-being are affected by climate change is an urgent matter.

Indexed as

Air PollutantsAir PollutionHypersensitivityAdolescentAllergensChildClimate ChangeHumansAir PollutantsAllergensAir pollutionAllergic diseasesAsthmaChildrenClimate changeRespiratory infections

Identifiers

PMID34896064
PMCPMC9510908
OpenAlexW4200107199

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.