Evidence map›Paper›PMID 34897297›Full record

ArticleBiomedical papers of the Medical Faculty of the University Palacky, Olomouc, Czechoslovakia2023

Pharmacotherapy of diabetes mellitus in patients with heart failure - a nation-wide analysis of contemporary treatment.

Marek Vicha, Tomas Skala, Libor Jelinek, Ludek Pavlu, Jiri Jarkovsky, Ladislav Dusek, Klara Benesova, Milos Taborsky

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Article in Biomedical papers of the Medical Faculty of the University Palacky, Olomouc, Czechoslovakia, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Trial
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Marek VichaDepartment of Medicine I - Cardiology, University Hospital Olomouc, Czech Republic.
Tomas SkalaDepartment of Medicine I - Cardiology, University Hospital Olomouc, Czech Republic.
Libor JelinekDepartment of Medicine I - Cardiology, University Hospital Olomouc, Czech Republic.
Ludek PavluDepartment of Medicine I - Cardiology, University Hospital Olomouc, Czech Republic.
Jiri JarkovskyInstitute of Health Information and Statistics of the Czech Republic, Palackeho nam. 4, P.O.BOX 60, Prague, Czech Republic.
Ladislav DusekInstitute of Health Information and Statistics of the Czech Republic, Palackeho nam. 4, P.O.BOX 60, Prague, Czech Republic.
Klara BenesovaInstitute of Health Information and Statistics of the Czech Republic, Palackeho nam. 4, P.O.BOX 60, Prague, Czech Republic.
Milos TaborskyDepartment of Medicine I - Cardiology, University Hospital Olomouc, Czech Republic.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimRetrospective national sub-analysis of antidiabetic pharmacotherapy in patients with diabetes mellitus (DM) and heart failure (HF) based on data reported to the National Register of Paid Health Services in the Czech Republic between 2012-2018. METHODOLOGY AND

resultsIn 2012, there were 75,022 patients with HF and DM (i.e. 42.5% of patients with HF), 6 years later 117,265 (i.e. 41.0% of HF patients in 2018). The most represented antidiabetic drug was metformin (45.6%). Of the insulins and analogues, glargine showed the largest positive trend (5.8% 2012; 14.8% 2018). Empagliflozin was the most prescribed SGLT-2 inhibitor (1.8% in 2018). A decrease in prescribing was observed for saxagliptin (0.5% 2012; 0.1% 2018) and for sulfonylurea derivates - gliclazide (13.0% 2012; 10.3% in 2018) and glimepiride (12.9% 2012; 9.0% 2018). Linagliptin was the most prescribed dipeptidyl peptidase inhibitor (0.7% 2012; 6.8% 2018).

conclusionIn the Czech Republic, between 2012 and 2008, there was an increase in prevalence of patients with heart failure and concomitant diabetes mellitus, their proportion being similar. In correspondence with other registries, metformin was used mostly. A positive trend was observed in prescription of DDP-4 and SGLT-2 inhibitors, while there was a significant decrease in patients taking sulfonylureas.

Indexed as

Diabetes Mellitus, Type 2Dipeptidyl-Peptidase IV InhibitorsHeart FailureMetforminSodium-Glucose Transporter 2 InhibitorsHumansHypoglycemic AgentsRetrospective StudiesDipeptidyl-Peptidase IV InhibitorsHypoglycemic AgentsMetforminSodium-Glucose Transporter 2 Inhibitorsdiabetes mellitusheart failureNational Register of Paid Health Services (NRHZS)pharmacotherapy

Identifiers

PMID34897297

What Socratic holds

Texttitle and abstract
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.