Evidence map›Paper›PMID 34897983›Full record

ArticleJournal of thrombosis and haemostasis : JTH2022

The plasminogen receptor Plg-R

Fahumiya Samad, Hongdong Bai, Nagyung Baik, Patrick Haider, Yuqing Zhang, Gersina Rega-Kaun, Christoph Kaun, Manfred Prager, Johann Wojta, Quyen Bui and 4 more

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of thrombosis and haemostasis : JTH, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.4field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Article
  3. Overexpression of Plg-RAdipocyte · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 8 institutions in 2 countries.

Fahumiya SamadDepartment of Cell Biology, San Diego Biomedical Research Institute, San Diego, California, USA.ORCID 0000-0001-7395-8605
Hongdong BaiDepartment of Medicine, Veterans Administration San Diego Healthcare System, San Diego, California, USA.
Nagyung BaikDepartment of Molecular Medicine, The Scripps Research Institute, La Jolla, California, USA.
Patrick HaiderDepartment of Internal Medicine II, Medical University of Vienna, Vienna, Austria.
Yuqing ZhangDepartment of Molecular Medicine, The Scripps Research Institute, La Jolla, California, USA.
Gersina Rega-KaunDepartment of Internal Medicine II, Medical University of Vienna, Vienna, Austria.
Christoph KaunDepartment of Internal Medicine II, Medical University of Vienna, Vienna, Austria.
Manfred PragerDepartment of Surgery, Hospital Oberwart, Oberwart, Austria.
Johann WojtaDepartment of Internal Medicine II, Medical University of Vienna, Vienna, Austria.
Quyen BuiDepartment of Cell Biology, San Diego Biomedical Research Institute, San Diego, California, USA.
Sagarika ChakrabartyDepartment of Cell Biology, San Diego Biomedical Research Institute, San Diego, California, USA.
Jing WangDepartment of Cell Biology, San Diego Biomedical Research Institute, San Diego, California, USA.
Robert J ParmerDepartment of Medicine, Veterans Administration San Diego Healthcare System, San Diego, California, USA.
Lindsey A MilesDepartment of Molecular Medicine, The Scripps Research Institute, La Jolla, California, USA.ORCID 0000-0002-0368-0895
San Diego Biomedical Research Institute · USScripps Research Institute · USMedical University of Vienna · ATKrankenhaus Oberndorf · ATLudwig Boltzmann Institute for Cancer Research · ATUniversity of California San Diego · USVA San Diego Healthcare System · USWilhelminen Hospital · AT

Funding

Regulation of plasminogen-dependent cell functions by the novel receptor, Plg-RKTR01HL081046 · NHLBI · SCRIPPS RESEARCH INSTITUTE, THE · PI MILES, LINDSEY A · 2007 to 2024
$8.7M
A Novel Plasminogen Receptor Promotes Adipose Function and Metabolic HomeostasisR01HL149511 · NHLBI · SCRIPPS RESEARCH INSTITUTE, THE · PI MILES, LINDSEY A, PARMER, ROBERT J · 2019 to 2022
$3.0M
Therapeutic Opportunities of Targeting Tissue Factor Signaling in ObesityR01HL104232 · NHLBI · TORREY PINES INST FOR MOLECULAR STUDIES · PI SAMAD, FAHUMIYA · 2011 to 2014
$2.4M
Regulation of Renal Injury and Fibrosis by the Plasminogen Receptor, Plg-RKTI01BX003933 · VA · VA SAN DIEGO HEALTHCARE SYSTEM · PI PARMER, ROBERT J · 2018 to 2021
–
BLRD VA I01 BX003933NHLBI NIH HHS R01 HL081046NHLBI NIH HHS R01 HL104232NHLBI NIH HHS R01 HL149511
6 · The paper itself

Abstract

backgroundPlg-R

objectivesWe investigated the role of Plg-R

methodsWe used adipose tissue (AT) sections from bariatric surgery patients and from high fat diet (HFD)-induced obese mice together with immunofluorescence and real-time polymerase chain reaction to study adipose expression of Plg-R

resultsPlg-R

conclusionsPlg-R

Indexed as

Adipose TissueHomeostasisReceptors, Cell SurfaceAnimalsDiabetes Mellitus, Type 2Dietary FatsFibrosisGlucose Tolerance TestHumansInflammationInsulin ResistanceMicePlasminogenDietary FatsPlasminogenPLGRKT protein, humanPLG-R(KT) protein, mouseReceptors, Cell Surfaceadipose inflammationhepatic steatosisinsulin resistanceobesityPlg-RKT

Identifiers

PMID34897983
PMCPMC8885904
OpenAlexW4200220077

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.